Explore Cytohesin 2/CYTH2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
| Target ID |
GM-MP2073
|
| Target Name |
Cytohesin 2/CYTH2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9266
|
| Gene ID |
100053821 (Equus caballus), 101089480 (Felis catus), 116692 (Rattus norvegicus), 19158 (Mus musculus)
476423 (Canis lupus familiaris), 718682 (Macaca mulatta), 768035 (Bos taurus), 9266 (Homo sapiens)
|
| Target Alternative Names |
ARF exchange factor,ARF nucleotide-binding site opener (Protein ARNO),ARNO,Arno,CLM2,CTS18,CTS18.1,CYTH2,Cyth2,Cytohesin 2,Cytohesin-2,PH,PSCD2,PSCD2L,Pscd2,SEC7 and coiled-coil domain-containing protein 2,SEC7L,Sec7,Sec7B,Sec7p-L,Sec7p-like,cytohesin-2
|
| Uniprot Accession |
P63035,P63034,Q2KI41,Q99418
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Phospholipase D signaling pathway, Pathogenic Escherichia coli infection
|
| Gene Ensembl |
ENSECAG00000009878, ENSMUSG00000003269, ENSCAFG00845001322, ENSMMUG00000001793, ENSBTAG00000001498, ENSG00000105443
|
Pre-made viral vector of Cytohesin 2/CYTH2 cDNA Clones/ORF Plasmid
Cytohesin 2/CYTH2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9266 | Pre-made Human CYTH2/ARNO/CTS18 siRNA oligo Duplex | 9266 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116692 | Pre-made Rat Cyth2/Arno/CLM2 siRNA oligo Duplex | 116692 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19158 | Pre-made Mouse Cyth2/ARNO/CLM2 siRNA oligo Duplex | 19158 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718682 | Pre-made Cynomolgus/Rhesus macaque CYTH2 siRNA oligo Duplex | 718682 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089480 | Pre-made Cat/Feline CYTH2 siRNA oligo Duplex | 101089480 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476423 | Pre-made Dog/Canine CYTH2/PSCD2 siRNA oligo Duplex | 476423 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo768035 | Pre-made Bovines/Cattle CYTH2/PSCD2 siRNA oligo Duplex | 768035 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053821 | Pre-made Equine/Horse CYTH2 siRNA oligo Duplex | 100053821 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cytohesin 2/CYTH2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2073-Ab | Human | Anti-Human Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2073-Ab | Rat | Anti-Rat Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2073-Ab | Mouse | Anti-Mouse Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2073-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2073-Ab | Cat/Feline | Anti-Cat/Feline Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2073-Ab | Dog/Canine | Anti-Dog/Canine Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2073-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2073-Ab | Equine/Horse | Anti-Equine/Horse Cytohesin 2/CYTH2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Cytohesin 2/CYTH2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2073-Ag | Human | Human Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2073-Ag | Rat | Rat Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2073-Ag | Mouse | Mouse Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2073-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2073-Ag | Cat/Feline | Cat/Feline Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2073-Ag | Dog/Canine | Dog/Canine Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2073-Ag | Bovines/Cattle | Bovines/Cattle Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2073-Ag | Equine/Horse | Equine/Horse Cytohesin 2/CYTH2 VLP (virus-like particle) | HEK293 | Products Developing |
