Explore Alpha E-Catenin/CTNNA1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]
| Target ID |
GM-MP2069
|
| Target Name |
Alpha E-Catenin/CTNNA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1495
|
| Gene ID |
100072548 (Equus caballus), 101089324 (Felis catus), 12385 (Mus musculus), 1495 (Homo sapiens)
307505 (Rattus norvegicus), 474698 (Canis lupus familiaris), 526848 (Bos taurus), 574385 (Macaca mulatta)
|
| Target Alternative Names |
2010010M04Rik,Alpha E-Catenin,Alpha E-catenin,CAP102,CTNNA1,Cadherin-associated protein,Catenin alpha-1,Catna1,Ctnna1,MDBS2,MDPT2,Renal carcinoma antigen NY-REN-13
|
| Uniprot Accession |
P26231,P35221,Q3MHM6
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
cancer
|
| Disease from KEGG |
Hippo signaling pathway, Adherens junction, Leukocyte transendothelial migration, Pathways in cancer, Endometrial cancer, Gastric cancer, Arrhythmogenic right ventricular cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000023991, ENSMUSG00000037815, ENSG00000044115, ENSCAFG00845022250, ENSBTAG00000014182, ENSMMUG00000017985
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Alpha E-Catenin/CTNNA1 cDNA Clones/ORF Plasmid
Alpha E-Catenin/CTNNA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1495 | Pre-made Human CTNNA1/MDBS2/MDPT2 siRNA oligo Duplex | 1495 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo307505 | Pre-made Rat Ctnna1/Catna1 siRNA oligo Duplex | 307505 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12385 | Pre-made Mouse Ctnna1/Catna1/2010010M04Rik siRNA oligo Duplex | 12385 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574385 | Pre-made Cynomolgus/Rhesus macaque CTNNA1 siRNA oligo Duplex | 574385 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089324 | Pre-made Cat/Feline CTNNA1 siRNA oligo Duplex | 101089324 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474698 | Pre-made Dog/Canine CTNNA1 siRNA oligo Duplex | 474698 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526848 | Pre-made Bovines/Cattle CTNNA1 siRNA oligo Duplex | 526848 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072548 | Pre-made Equine/Horse CTNNA1 siRNA oligo Duplex | 100072548 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Alpha E-Catenin/CTNNA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2069-Ab | Human | Anti-Human Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2069-Ab | Rat | Anti-Rat Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2069-Ab | Mouse | Anti-Mouse Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2069-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2069-Ab | Cat/Feline | Anti-Cat/Feline Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2069-Ab | Dog/Canine | Anti-Dog/Canine Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2069-Ab | Bovines/Cattle | Anti-Bovines/Cattle Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2069-Ab | Equine/Horse | Anti-Equine/Horse Alpha E-Catenin/CTNNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Alpha E-Catenin/CTNNA1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2069-Ag | Human | Human Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2069-Ag | Rat | Rat Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2069-Ag | Mouse | Mouse Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2069-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2069-Ag | Cat/Feline | Cat/Feline Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2069-Ag | Dog/Canine | Dog/Canine Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2069-Ag | Bovines/Cattle | Bovines/Cattle Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2069-Ag | Equine/Horse | Equine/Horse Alpha E-Catenin/CTNNA1 VLP (virus-like particle) | HEK293 | Products Developing |
