Explore IRSp53/BAIAP2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]
Target ID |
GM-MP2015
|
Target Name |
IRSp53/BAIAP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10458
|
Gene ID |
100050207 (Equus caballus), 100428388 (Macaca mulatta), 101087366 (Felis catus), 10458 (Homo sapiens) 108100 (Mus musculus), 117542 (Rattus norvegicus), 403473 (Canis lupus familiaris), 507837 (Bos taurus)
|
Target Alternative Names |
BAIAP2,Baiap2,BAP2,WAML,FLAF3,IRSP53,IRSp53,Irsp53,IRSP53S
|
Uniprot Accession |
Q9UQB8,Q8BKX1,Q6GMN2,Q5EAD0
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
|
Disease |
|
Disease from KEGG |
Adherens junction, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Yersinia infection
|
Gene Ensembl |
ENSECAG00000022150, ENSMMUG00000015512, ENSG00000175866, ENSMUSG00000025372, ENSCAFG00845011762, ENSBTAG00000019044
|
Target Classification |
|
IRSp53/BAIAP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo10458 | Pre-made Human BAIAP2/BAP2/WAML siRNA oligo Duplex | 10458 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo117542 | Pre-made Rat Baiap2/Irsp53 siRNA oligo Duplex | 117542 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo108100 | Pre-made Mouse Baiap2/IRSp53 siRNA oligo Duplex | 108100 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo100428388 | Pre-made Cynomolgus/Rhesus macaque BAIAP2 siRNA oligo Duplex | 100428388 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101087366 | Pre-made Cat/Feline BAIAP2 siRNA oligo Duplex | 101087366 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo403473 | Pre-made Dog/Canine BAIAP2/IRSP53S siRNA oligo Duplex | 403473 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo507837 | Pre-made Bovines/Cattle BAIAP2 siRNA oligo Duplex | 507837 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100050207 | Pre-made Equine/Horse BAIAP2 siRNA oligo Duplex | 100050207 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IRSp53/BAIAP2 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-MP2015-Ab | Human | Anti-Human IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-rg-MP2015-Ab | Rat | Anti-Rat IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-mg-MP2015-Ab | Mouse | Anti-Mouse IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cynog-MP2015-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-felg-MP2015-Ab | Cat/Feline | Anti-Cat/Feline IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cang-MP2015-Ab | Dog/Canine | Anti-Dog/Canine IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-bovg-MP2015-Ab | Bovines/Cattle | Anti-Bovines/Cattle IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-equg-MP2015-Ab | Equine/Horse | Anti-Equine/Horse IRSp53/BAIAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
IRSp53/BAIAP2 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-MP2015-Ag | Human | Human IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-MP2015-Ag | Rat | Rat IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-MP2015-Ag | Mouse | Mouse IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-MP2015-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-MP2015-Ag | Cat/Feline | Cat/Feline IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-MP2015-Ag | Dog/Canine | Dog/Canine IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-MP2015-Ag | Bovines/Cattle | Bovines/Cattle IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-MP2015-Ag | Equine/Horse | Equine/Horse IRSp53/BAIAP2 VLP (virus-like particle) | HEK293 | Products Developing |