Explore ARHGEF1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2001
|
| Target Name |
ARHGEF1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9138
|
| Gene ID |
100856354 (Canis lupus familiaris), 101083892 (Felis catus), 102150569 (Equus caballus), 16801 (Mus musculus)
513377 (Bos taurus), 60323 (Rattus norvegicus), 722198 (Macaca mulatta), 9138 (Homo sapiens)
|
| Target Alternative Names |
115 kDa guanine nucleotide exchange factor (p115-RhoGEF,ARHGEF1,Arhgef1,GEF1,IMD62,LBCL2,LSC,Lbcl2,Lsc,P115-RHOGEF,Rho guanine nucleotide exchange factor 1,SUB1.5,Sub1.5,p115RhoGEF)
|
| Uniprot Accession |
Q61210,Q9Z1I6,Q92888
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Vascular smooth muscle contraction, Platelet activation, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Pathogenic Escherichia coli infection, Yersinia infection, Human cytomegalovirus infection, Pathways in cancer, Proteoglycans in cancer, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSCAFG00845001568, ENSECAG00000035888, ENSMUSG00000040940, ENSBTAG00000018912, ENSMMUG00000022305, ENSG00000076928
|
| Target Classification |
Tumor-associated antigen (TAA)
|
ARHGEF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9138 | Pre-made Human ARHGEF1/LSC/GEF1 siRNA oligo Duplex | 9138 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60323 | Pre-made Rat Arhgef1/Lsc/Lbcl2 siRNA oligo Duplex | 60323 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16801 | Pre-made Mouse Arhgef1/Lsc/Lbcl2 siRNA oligo Duplex | 16801 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722198 | Pre-made Cynomolgus/Rhesus macaque ARHGEF1 siRNA oligo Duplex | 722198 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083892 | Pre-made Cat/Feline ARHGEF1 siRNA oligo Duplex | 101083892 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856354 | Pre-made Dog/Canine ARHGEF1 siRNA oligo Duplex | 100856354 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513377 | Pre-made Bovines/Cattle ARHGEF1 siRNA oligo Duplex | 513377 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102150569 | Pre-made Equine/Horse ARHGEF1 siRNA oligo Duplex | 102150569 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ARHGEF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2001-Ab | Human | Anti-Human ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2001-Ab | Rat | Anti-Rat ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP2001-Ab | Mouse | Anti-Mouse ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2001-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2001-Ab | Cat/Feline | Anti-Cat/Feline ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP2001-Ab | Dog/Canine | Anti-Dog/Canine ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2001-Ab | Bovines/Cattle | Anti-Bovines/Cattle ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2001-Ab | Equine/Horse | Anti-Equine/Horse ARHGEF1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ARHGEF1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2001-Ag | Human | Human ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2001-Ag | Rat | Rat ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2001-Ag | Mouse | Mouse ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2001-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2001-Ag | Cat/Feline | Cat/Feline ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2001-Ag | Dog/Canine | Dog/Canine ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2001-Ag | Bovines/Cattle | Bovines/Cattle ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2001-Ag | Equine/Horse | Equine/Horse ARHGEF1 VLP (virus-like particle) | HEK293 | Products Developing |
