Explore AP50/AP2M1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]
| Target ID |
GM-MP1993
|
| Target Name |
AP50/AP2M1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1173
|
| Gene ID |
100058961 (Equus caballus), 101088686 (Felis catus), 116563 (Rattus norvegicus), 1173 (Homo sapiens)
11773 (Mus musculus), 517446 (Bos taurus), 607139 (Canis lupus familiaris), 703554 (Macaca mulatta)
|
| Target Alternative Names |
AP-2 complex subunit mu,AP-2 mu chain,AP2M1,AP50,Adaptin-mu2,Adaptor protein complex AP-2 subunit mu,Adaptor-related protein complex 2 subunit mu,Ap2m1,Ap50,CLAPM1,Clapm1,Clathrin assembly protein complex 2 mu medium chain,Clathrin coat assembly protein AP50,Clathrin coat-associated protein AP50,HA2 50 kDa subunit,MRD60,Plasma membrane adaptor AP-2 50 kDa protein,mu2
|
| Uniprot Accession |
P84092,Q96CW1,P84091,Q3ZC13
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSECAG00000000242, ENSG00000161203, ENSMUSG00000022841, ENSBTAG00000020106, ENSCAFG00845026562, ENSMMUG00000006557
|
Pre-made viral vector of AP50/AP2M1 cDNA Clones/ORF Plasmid
AP50/AP2M1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1173 | Pre-made Human AP2M1/mu2/AP50 siRNA oligo Duplex | 1173 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116563 | Pre-made Rat Ap2m1/mu2/Ap50 siRNA oligo Duplex | 116563 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11773 | Pre-made Mouse Ap2m1 siRNA oligo Duplex | 11773 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703554 | Pre-made Cynomolgus/Rhesus macaque AP2M1 siRNA oligo Duplex | 703554 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088686 | Pre-made Cat/Feline AP2M1 siRNA oligo Duplex | 101088686 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607139 | Pre-made Dog/Canine AP2M1 siRNA oligo Duplex | 607139 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo517446 | Pre-made Bovines/Cattle AP2M1 siRNA oligo Duplex | 517446 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058961 | Pre-made Equine/Horse AP2M1 siRNA oligo Duplex | 100058961 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AP50/AP2M1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1993-Ab | Human | Anti-Human AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1993-Ab | Rat | Anti-Rat AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1993-Ab | Mouse | Anti-Mouse AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1993-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1993-Ab | Cat/Feline | Anti-Cat/Feline AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1993-Ab | Dog/Canine | Anti-Dog/Canine AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1993-Ab | Bovines/Cattle | Anti-Bovines/Cattle AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1993-Ab | Equine/Horse | Anti-Equine/Horse AP50/AP2M1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
AP50/AP2M1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1993-Ag | Human | Human AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1993-Ag | Rat | Rat AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1993-Ag | Mouse | Mouse AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1993-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1993-Ag | Cat/Feline | Cat/Feline AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1993-Ag | Dog/Canine | Dog/Canine AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1993-Ag | Bovines/Cattle | Bovines/Cattle AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1993-Ag | Equine/Horse | Equine/Horse AP50/AP2M1 VLP (virus-like particle) | HEK293 | Products Developing |
