Explore ANK2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]
| Target ID |
GM-MP1988
|
| Target Name |
ANK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
287
|
| Gene ID |
100064198 (Equus caballus), 101100129 (Felis catus), 109676 (Mus musculus), 287 (Homo sapiens)
362036 (Rattus norvegicus), 487908 (Canis lupus familiaris), 539238 (Bos taurus), 702180 (Macaca mulatta)
|
| Target Alternative Names |
100043364,ANK-2,ANK2,ANKB,Ank-2,Ank2,Ank3,Ankyrin-2,Ankyrin-B,Brain ankyrin,CFAP87,FAP87,Gm4392,LQT4,Non-erythroid ankyrin,brank-2
|
| Uniprot Accession |
Q8C8R3,Q01484
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000024436, ENSMUSG00000032826, ENSG00000145362, ENSCAFG00845020611, ENSBTAG00000002392, ENSMMUG00000008633
|
ANK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo287 | Pre-made Human ANK2/LQT4/ANK-2 siRNA oligo Duplex | 287 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362036 | Pre-made Rat Ank2/Ank3 siRNA oligo Duplex | 362036 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109676 | Pre-made Mouse Ank2/Ank-2/Gm4392 siRNA oligo Duplex | 109676 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702180 | Pre-made Cynomolgus/Rhesus macaque ANK2 siRNA oligo Duplex | 702180 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100129 | Pre-made Cat/Feline ANK2 siRNA oligo Duplex | 101100129 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487908 | Pre-made Dog/Canine ANK2/ANKB siRNA oligo Duplex | 487908 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539238 | Pre-made Bovines/Cattle ANK2 siRNA oligo Duplex | 539238 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064198 | Pre-made Equine/Horse ANK2 siRNA oligo Duplex | 100064198 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ANK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1988-Ab | Human | Anti-Human ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1988-Ab | Rat | Anti-Rat ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1988-Ab | Mouse | Anti-Mouse ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1988-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1988-Ab | Cat/Feline | Anti-Cat/Feline ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1988-Ab | Dog/Canine | Anti-Dog/Canine ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1988-Ab | Bovines/Cattle | Anti-Bovines/Cattle ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1988-Ab | Equine/Horse | Anti-Equine/Horse ANK2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ANK2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1988-Ag | Human | Human ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1988-Ag | Rat | Rat ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1988-Ag | Mouse | Mouse ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1988-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1988-Ag | Cat/Feline | Cat/Feline ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1988-Ag | Dog/Canine | Dog/Canine ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1988-Ag | Bovines/Cattle | Bovines/Cattle ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1988-Ag | Equine/Horse | Equine/Horse ANK2 VLP (virus-like particle) | HEK293 | Products Developing |
