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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
| Target ID |
GM-MP1973
|
| Target Name |
ADH1B
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
125
|
| Gene ID |
125 (Homo sapiens)
|
| Target Alternative Names |
ADH1B,ADH2,Alcohol dehydrogenase 1B,Alcohol dehydrogenase subunit beta,All-trans-retinol dehydrogenase [NAD(+)] ADH1B,HEL-S-117
|
| Uniprot Accession |
P00325
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Alcoholic liver disease, Retinol metabolism, Drug metabolism - cytochrome P450
|
| Gene Ensembl |
ENSG00000196616
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ADH1B cDNA Clones/ORF Plasmid
ADH1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo125 | Pre-made Human ADH1B/ADH2/HEL-S-117 siRNA oligo Duplex | 125 | Human | In-vitro grade; in-vivo grade | Detail |
ADH1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1973-Ab | Human | Anti-Human ADH1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ADH1B VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1973-Ag | Human | Human ADH1B VLP (virus-like particle) | HEK293 | Products Developing |