Explore XCR1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2020]
| Target ID |
GM-MP1940
|
| Target Name |
XCR1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2829
|
| Gene ID |
100065485 (Equus caballus), 111558429 (Felis catus), 23832 (Mus musculus), 2829 (Homo sapiens)
301086 (Rattus norvegicus), 484792 (Canis lupus familiaris), 617880 (Bos taurus), 713622 (Macaca mulatta)
|
| Target Alternative Names |
CCXCR1,Ccxcr1,Chemokine XC receptor 1,G-protein coupled receptor 5,GPR5,Gpr5,Lymphotactin receptor,XC chemokine receptor 1,XCR1,Xcr1,mXcr1
|
| Uniprot Accession |
Q9R0M1,P46094
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000002984, ENSG00000173578, ENSCAFG00845012202, ENSBTAG00000063018, ENSMMUG00000023584
|
| Target Classification |
GPCR
|
Pre-made viral vector of XCR1 cDNA Clones/ORF Plasmid
XCR1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2829 | Pre-made Human XCR1/GPR5/CCXCR1 siRNA oligo Duplex | 2829 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo301086 | Pre-made Rat Xcr1 siRNA oligo Duplex | 301086 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23832 | Pre-made Mouse Xcr1/Gpr5/mXcr1 siRNA oligo Duplex | 23832 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo713622 | Pre-made Cynomolgus/Rhesus macaque XCR1 siRNA oligo Duplex | 713622 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111558429 | Pre-made Cat/Feline XCR1 siRNA oligo Duplex | 111558429 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484792 | Pre-made Dog/Canine XCR1 siRNA oligo Duplex | 484792 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617880 | Pre-made Bovines/Cattle XCR1 siRNA oligo Duplex | 617880 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065485 | Pre-made Equine/Horse XCR1 siRNA oligo Duplex | 100065485 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
XCR1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1940-Ab | Human | Anti-Human XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP1940-Ab | Rat | Anti-Rat XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP1940-Ab | Mouse | Anti-Mouse XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP1940-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP1940-Ab | Cat/Feline | Anti-Cat/Feline XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP1940-Ab | Dog/Canine | Anti-Dog/Canine XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP1940-Ab | Bovines/Cattle | Anti-Bovines/Cattle XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP1940-Ab | Equine/Horse | Anti-Equine/Horse XCR1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
XCR1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1940-Ag | Human | Human XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1940-Ag | Rat | Rat XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1940-Ag | Mouse | Mouse XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1940-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1940-Ag | Cat/Feline | Cat/Feline XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1940-Ag | Dog/Canine | Dog/Canine XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1940-Ag | Bovines/Cattle | Bovines/Cattle XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1940-Ag | Equine/Horse | Equine/Horse XCR1 VLP (virus-like particle) | HEK293 | Products Developing |
