Explore WNT6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP1938
|
| Target Name |
WNT6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7475
|
| Gene ID |
100058824 (Equus caballus), 101099392 (Felis catus), 22420 (Mus musculus), 316526 (Rattus norvegicus)
488527 (Canis lupus familiaris), 505075 (Bos taurus), 700573 (Macaca mulatta), 7475 (Homo sapiens)
|
| Target Alternative Names |
Protein Wnt-6,WNT6,Wnt-6,Wnt6
|
| Uniprot Accession |
P22727,Q9Y6F9
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Wnt signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Melanogenesis, Cushing syndrome, Alzheimer disease, Human papillomavirus infection, Pathways in cancer, Proteoglycans in cancer, Basal cell carcinoma, Breast cancer, Hepatocellular carcinoma, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000013092, ENSMUSG00000033227, ENSCAFG00845028514, ENSMMUG00000052954, ENSG00000115596
|
Pre-made viral vector of WNT6 cDNA Clones/ORF Plasmid
WNT6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7475 | Pre-made Human WNT6 siRNA oligo Duplex | 7475 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo316526 | Pre-made Rat Wnt6 siRNA oligo Duplex | 316526 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22420 | Pre-made Mouse Wnt6/Wnt-6 siRNA oligo Duplex | 22420 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700573 | Pre-made Cynomolgus/Rhesus macaque WNT6 siRNA oligo Duplex | 700573 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099392 | Pre-made Cat/Feline WNT6 siRNA oligo Duplex | 101099392 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488527 | Pre-made Dog/Canine WNT6 siRNA oligo Duplex | 488527 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505075 | Pre-made Bovines/Cattle WNT6 siRNA oligo Duplex | 505075 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058824 | Pre-made Equine/Horse WNT6 siRNA oligo Duplex | 100058824 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
WNT6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1938-Ab | Human | Anti-Human WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP1938-Ab | Rat | Anti-Rat WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP1938-Ab | Mouse | Anti-Mouse WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP1938-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP1938-Ab | Cat/Feline | Anti-Cat/Feline WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP1938-Ab | Dog/Canine | Anti-Dog/Canine WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP1938-Ab | Bovines/Cattle | Anti-Bovines/Cattle WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP1938-Ab | Equine/Horse | Anti-Equine/Horse WNT6 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
WNT6 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1938-Ag | Human | Human WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1938-Ag | Rat | Rat WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1938-Ag | Mouse | Mouse WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1938-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1938-Ag | Cat/Feline | Cat/Feline WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1938-Ag | Dog/Canine | Dog/Canine WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1938-Ag | Bovines/Cattle | Bovines/Cattle WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1938-Ag | Equine/Horse | Equine/Horse WNT6 VLP (virus-like particle) | HEK293 | Products Developing |
