Explore VNN2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
| Target ID |
GM-MP1928
|
| Target Name |
VNN2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8875
|
| Gene ID |
100067672 (Equus caballus), 534929 (Bos taurus), 8875 (Homo sapiens)
|
| Target Alternative Names |
FOAP-4,GPI-80,Glycosylphosphatidyl inositol-anchored protein GPI-80,Pantetheine hydrolase VNN2,Protein FOAP-4,VNN2,Vascular non-inflammatory molecule 2 (Vanin-2)
|
| Uniprot Accession |
O95498
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000055048, ENSBTAG00000016357, ENSG00000112303
|
VNN2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8875 | Pre-made Human VNN2/FOAP-4/GPI-80 siRNA oligo Duplex | 8875 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534929 | Pre-made Bovines/Cattle VNN2 siRNA oligo Duplex | 534929 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067672 | Pre-made Equine/Horse VNN2 siRNA oligo Duplex | 100067672 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VNN2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1928-Ab | Human | Anti-Human VNN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1928-Ab | Bovines/Cattle | Anti-Bovines/Cattle VNN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1928-Ab | Equine/Horse | Anti-Equine/Horse VNN2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
VNN2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1928-Ag | Human | Human VNN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1928-Ag | Bovines/Cattle | Bovines/Cattle VNN2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1928-Ag | Equine/Horse | Equine/Horse VNN2 VLP (virus-like particle) | HEK293 | Products Developing |
