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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24. [provided by RefSeq, Feb 2009]
| Target ID |
GM-MP1927
|
| Target Name |
VNN1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8876
|
| Gene ID |
100146975 (Equus caballus), 22361 (Mus musculus), 29142 (Rattus norvegicus), 526704 (Bos taurus)
8876 (Homo sapiens)
|
| Target Alternative Names |
HDLCQ8,Pantetheinase,Pantetheine hydrolase,Tiff66,V-1,VNN1,Vascular non-inflammatory molecule 1 (Vanin-1),Vnn1
|
| Uniprot Accession |
Q9Z0K8,Q58CQ9,O95497
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000022135, ENSMUSG00000037440, ENSBTAG00000015094, ENSG00000112299
|
VNN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8876 | Pre-made Human VNN1/HDLCQ8/Tiff66 siRNA oligo Duplex | 8876 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29142 | Pre-made Rat Vnn1/Tiff66 siRNA oligo Duplex | 29142 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22361 | Pre-made Mouse Vnn1/V-1 siRNA oligo Duplex | 22361 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526704 | Pre-made Bovines/Cattle VNN1 siRNA oligo Duplex | 526704 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146975 | Pre-made Equine/Horse VNN1 siRNA oligo Duplex | 100146975 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VNN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1927-Ab | Human | Anti-Human VNN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1927-Ab | Rat | Anti-Rat VNN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1927-Ab | Mouse | Anti-Mouse VNN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1927-Ab | Bovines/Cattle | Anti-Bovines/Cattle VNN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1927-Ab | Equine/Horse | Anti-Equine/Horse VNN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
VNN1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1927-Ag | Human | Human VNN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1927-Ag | Rat | Rat VNN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1927-Ag | Mouse | Mouse VNN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1927-Ag | Bovines/Cattle | Bovines/Cattle VNN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1927-Ag | Equine/Horse | Equine/Horse VNN1 VLP (virus-like particle) | HEK293 | Products Developing |
