Explore UPK1A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Target ID |
GM-MP1907
|
Target Name |
UPK1A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
11045
|
Gene ID |
100051323 (Equus caballus), 101099514 (Felis catus), 109637 (Mus musculus), 11045 (Homo sapiens) 282112 (Bos taurus), 365227 (Rattus norvegicus), 484579 (Canis lupus familiaris), 710131 (Macaca mulatta)
|
Target Alternative Names |
UPK1A,Upk1a,Upk1,Tspan21,1110031P12Rik,UP1A,UPIA,UPKA,TSPAN21
|
Uniprot Accession |
Q9D132,O00322,P38572
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000012871, ENSMUSG00000006313, ENSG00000105668, ENSBTAG00000020543, ENSCAFG00845001931, ENSMMUG00000006711
|
Target Classification |
|
UPK1A siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo11045 | Pre-made Human UPK1A/UP1A/UPIA siRNA oligo Duplex | 11045 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo365227 | Pre-made Rat Upk1a siRNA oligo Duplex | 365227 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo109637 | Pre-made Mouse Upk1a/Upk1/Tspan21 siRNA oligo Duplex | 109637 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo710131 | Pre-made Cynomolgus/Rhesus macaque UPK1A siRNA oligo Duplex | 710131 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101099514 | Pre-made Cat/Feline UPK1A siRNA oligo Duplex | 101099514 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo484579 | Pre-made Dog/Canine UPK1A siRNA oligo Duplex | 484579 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo282112 | Pre-made Bovines/Cattle UPK1A siRNA oligo Duplex | 282112 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100051323 | Pre-made Equine/Horse UPK1A siRNA oligo Duplex | 100051323 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
UPK1A antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-MP1907-Ab | Human | Anti-Human UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-rg-MP1907-Ab | Rat | Anti-Rat UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-mg-MP1907-Ab | Mouse | Anti-Mouse UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cynog-MP1907-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-felg-MP1907-Ab | Cat/Feline | Anti-Cat/Feline UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cang-MP1907-Ab | Dog/Canine | Anti-Dog/Canine UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-bovg-MP1907-Ab | Bovines/Cattle | Anti-Bovines/Cattle UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-equg-MP1907-Ab | Equine/Horse | Anti-Equine/Horse UPK1A monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
UPK1A VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-MP1907-Ag | Human | Human UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-MP1907-Ag | Rat | Rat UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-MP1907-Ag | Mouse | Mouse UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-MP1907-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-MP1907-Ag | Cat/Feline | Cat/Feline UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-MP1907-Ag | Dog/Canine | Dog/Canine UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-MP1907-Ag | Bovines/Cattle | Bovines/Cattle UPK1A VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-MP1907-Ag | Equine/Horse | Equine/Horse UPK1A VLP (virus-like particle) | HEK293 | Products Developing |