Explore UNC5B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]
| Target ID |
GM-MP1902
|
| Target Name |
UNC5B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
219699
|
| Gene ID |
100072764 (Equus caballus), 101101167 (Felis catus), 107449 (Mus musculus), 219699 (Homo sapiens)
479239 (Canis lupus familiaris), 524942 (Bos taurus), 60630 (Rattus norvegicus), 715786 (Macaca mulatta)
|
| Target Alternative Names |
6330415E02Rik,A630020F16,D10Bwg0792e,Netrin receptor UNC5B,Protein unc-5 homolog 2,Protein unc-5 homolog B,UNC5B,UNC5H2,Unc5b,Unc5h2,p53-regulated receptor for death and life protein 1 (p53RDL1),p53RDL1
|
| Uniprot Accession |
Q8K1S3,Q8IZJ1,O08722
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000009792, ENSMUSG00000020099, ENSG00000107731, ENSCAFG00845004449, ENSBTAG00000014270, ENSMMUG00000005998
|
UNC5B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo219699 | Pre-made Human UNC5B/UNC5H2/p53RDL1 siRNA oligo Duplex | 219699 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60630 | Pre-made Rat Unc5b/Unc5h2 siRNA oligo Duplex | 60630 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo107449 | Pre-made Mouse Unc5b/Unc5h2/A630020F16 siRNA oligo Duplex | 107449 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715786 | Pre-made Cynomolgus/Rhesus macaque UNC5B siRNA oligo Duplex | 715786 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101167 | Pre-made Cat/Feline UNC5B siRNA oligo Duplex | 101101167 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479239 | Pre-made Dog/Canine UNC5B siRNA oligo Duplex | 479239 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524942 | Pre-made Bovines/Cattle UNC5B siRNA oligo Duplex | 524942 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072764 | Pre-made Equine/Horse UNC5B siRNA oligo Duplex | 100072764 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
UNC5B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1902-Ab | Human | Anti-Human UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1902-Ab | Rat | Anti-Rat UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1902-Ab | Mouse | Anti-Mouse UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1902-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1902-Ab | Cat/Feline | Anti-Cat/Feline UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1902-Ab | Dog/Canine | Anti-Dog/Canine UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1902-Ab | Bovines/Cattle | Anti-Bovines/Cattle UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1902-Ab | Equine/Horse | Anti-Equine/Horse UNC5B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
UNC5B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1902-Ag | Human | Human UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1902-Ag | Rat | Rat UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1902-Ag | Mouse | Mouse UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1902-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1902-Ag | Cat/Feline | Cat/Feline UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1902-Ag | Dog/Canine | Dog/Canine UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1902-Ag | Bovines/Cattle | Bovines/Cattle UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1902-Ag | Equine/Horse | Equine/Horse UNC5B VLP (virus-like particle) | HEK293 | Products Developing |
