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Target
sublocation: Transmembrane Protein.
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015]
Target ID |
GM-MP1899
|
Target Name |
ULBP2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
80328
|
Gene ID |
80328 (Homo sapiens)
|
Target Alternative Names |
ULBP2,N2DL2,RAET1H,RAET1L,NKG2DL2,ALCAN-alpha
|
Uniprot Accession |
Q9BZM5
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
|
Disease |
cancer
|
Disease from KEGG |
Natural killer cell mediated cytotoxicity
|
Gene Ensembl |
ENSG00000131015
|
Target Classification |
|
Pre-made viral vector of ULBP2 cDNA Clones/ORF Plasmid
ULBP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo80328 | Pre-made Human ULBP2/N2DL2/RAET1H siRNA oligo Duplex | 80328 | Human | In-vitro grade; in-vivo grade | Detail |
ULBP2 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-MP1899-Ab | Human | Anti-Human ULBP2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ULBP2 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-MP1899-Ag | Human | Human ULBP2 VLP (virus-like particle) | HEK293 | Products Developing |