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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
| Target ID |
GM-MP1898
|
| Target Name |
ULBP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
80329
|
| Gene ID |
120100095 (Rattus norvegicus), 77777 (Mus musculus), 80329 (Homo sapiens)
|
| Target Alternative Names |
A430108B07Rik,ALCAN-beta,LOC120100095,MULT1,N2DL-1,NKG2D ligand 1 (N2DL-1,NKG2DL1,NKG2DL1),RAET1I,Retinoic acid early transcript 1I,UL16-binding protein 1,ULBP1,Ulbp1
|
| Uniprot Accession |
Q9BZM6
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity
|
| Gene Ensembl |
ENSMUSG00000079685, ENSG00000111981
|
Pre-made viral vector of ULBP1 cDNA Clones/ORF Plasmid
ULBP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo80329 | Pre-made Human ULBP1/N2DL-1/RAET1I siRNA oligo Duplex | 80329 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo120100095 | Pre-made Rat LOC120100095 siRNA oligo Duplex | 120100095 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo77777 | Pre-made Mouse Ulbp1/MULT1/A430108B07Rik siRNA oligo Duplex | 77777 | Mouse | In-vitro grade; in-vivo grade | Detail |
ULBP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1898-Ab | Human | Anti-Human ULBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1898-Ab | Rat | Anti-Rat ULBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1898-Ab | Mouse | Anti-Mouse ULBP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ULBP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1898-Ag | Human | Human ULBP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1898-Ag | Rat | Rat ULBP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1898-Ag | Mouse | Mouse ULBP1 VLP (virus-like particle) | HEK293 | Products Developing |