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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP1855
|
| Target Name |
DcR2/TNFRSF10D/CD264
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8793
|
| Gene ID |
716901 (Macaca mulatta), 8793 (Homo sapiens)
|
| Target Alternative Names |
CD264,DCR2,DcR2,Decoy receptor 2 (DcR2),TNF-related apoptosis-inducing ligand receptor 4 (TRAIL receptor 4,TNFRSF10D,TRAIL receptor with a truncated death domain,TRAIL-R4,TRAIL-R4),TRAILR4,TRUNDD,Tumor necrosis factor receptor superfamily member 10D
|
| Uniprot Accession |
Q9UBN6
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor
|
| Gene Ensembl |
ENSMMUG00000007542, ENSG00000173530
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of DcR2/TNFRSF10D/CD264 cDNA Clones/ORF Plasmid
DcR2/TNFRSF10D/CD264 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8793 | Pre-made Human TNFRSF10D/DCR2/CD264 siRNA oligo Duplex | 8793 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716901 | Pre-made Cynomolgus/Rhesus macaque TNFRSF10D siRNA oligo Duplex | 716901 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
DcR2/TNFRSF10D/CD264 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1855-Ab | Human | Anti-Human DcR2/TNFRSF10D/CD264 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1855-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DcR2/TNFRSF10D/CD264 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
DcR2/TNFRSF10D/CD264 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1855-Ag | Human | Human DcR2/TNFRSF10D/CD264 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1855-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DcR2/TNFRSF10D/CD264 VLP (virus-like particle) | HEK293 | Products Developing |