Explore TGFBI/BIGH3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP1793
|
| Target Name |
TGFBI/BIGH3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7045
|
| Gene ID |
100072674 (Equus caballus), 101081357 (Felis catus), 116487 (Rattus norvegicus), 21810 (Mus musculus)
481519 (Canis lupus familiaris), 539596 (Bos taurus), 7045 (Homo sapiens), 712503 (Macaca mulatta)
|
| Target Alternative Names |
TGFBI,Tgfbi,BIGH3,Big-h3,68kDa,big-h3,Beta-ig,MP70,MP78,CSD,CDB1,CDG2,CSD1,CSD2,CSD3,EBMD,LCD1,CDGG1
|
| Uniprot Accession |
P82198,P55906,Q15582
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease |
cancer, Pre-eclampsia
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000020193, ENSMUSG00000035493, ENSCAFG00845014380, ENSBTAG00000009513, ENSG00000120708, ENSMMUG00000000332
|
| Target Classification |
|
Pre-made viral vector of TGFBI/BIGH3 cDNA Clones/ORF Plasmid
TGFBI/BIGH3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7045 | Pre-made Human TGFBI/CSD/CDB1 siRNA oligo Duplex | 7045 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116487 | Pre-made Rat Tgfbi/BIGH3/Big-h3 siRNA oligo Duplex | 116487 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21810 | Pre-made Mouse Tgfbi/68kDa/big-h3 siRNA oligo Duplex | 21810 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712503 | Pre-made Cynomolgus/Rhesus macaque TGFBI siRNA oligo Duplex | 712503 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081357 | Pre-made Cat/Feline TGFBI siRNA oligo Duplex | 101081357 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481519 | Pre-made Dog/Canine TGFBI siRNA oligo Duplex | 481519 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539596 | Pre-made Bovines/Cattle TGFBI/MP70/MP78 siRNA oligo Duplex | 539596 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072674 | Pre-made Equine/Horse TGFBI siRNA oligo Duplex | 100072674 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TGFBI/BIGH3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1793-Ab | Human | Anti-Human TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP1793-Ab | Rat | Anti-Rat TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP1793-Ab | Mouse | Anti-Mouse TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP1793-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP1793-Ab | Cat/Feline | Anti-Cat/Feline TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP1793-Ab | Dog/Canine | Anti-Dog/Canine TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP1793-Ab | Bovines/Cattle | Anti-Bovines/Cattle TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP1793-Ab | Equine/Horse | Anti-Equine/Horse TGFBI/BIGH3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
TGFBI/BIGH3 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1793-Ag | Human | Human TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1793-Ag | Rat | Rat TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1793-Ag | Mouse | Mouse TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1793-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1793-Ag | Cat/Feline | Cat/Feline TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1793-Ag | Dog/Canine | Dog/Canine TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1793-Ag | Bovines/Cattle | Bovines/Cattle TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1793-Ag | Equine/Horse | Equine/Horse TGFBI/BIGH3 VLP (virus-like particle) | HEK293 | Products Developing |
