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Target
sublocation: Transmembrane Protein.
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant). [provided by RefSeq, Oct 2009]
| Target ID |
GM-MP1768
|
| Target Name |
TAS2R38
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5726
|
| Gene ID |
100271737 (Canis lupus familiaris), 101084695 (Felis catus), 106783090 (Equus caballus), 387513 (Mus musculus) 500091 (Rattus norvegicus), 5726 (Homo sapiens), 695549 (Macaca mulatta), 787789 (Bos taurus)
|
| Target Alternative Names |
CAFA-T2R38,Mamu-T2R38,PTC,PTC bitter taste receptor,T2R138,T2R38,T2R61,TAS2R38,THIOT,Tas2r138,Tas2r38,Taste receptor type 2 member 38,Taste receptor type 2 member 61 (T2R61),mt2r31
|
| Uniprot Accession |
Q7TQA6,Q4VHE7,P59533
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Taste transduction
|
| Gene Ensembl |
ENSCAFG00845030800, ENSMUSG00000058250, ENSG00000257138, ENSMMUG00000055710
|
Pre-made viral vector of TAS2R38 cDNA Clones/ORF Plasmid
TAS2R38 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5726 | Pre-made Human TAS2R38/PTC/T2R38 siRNA oligo Duplex | 5726 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500091 | Pre-made Rat Tas2r138/T2R38/Tas2r38 siRNA oligo Duplex | 500091 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo387513 | Pre-made Mouse Tas2r138/T2R38/T2R138 siRNA oligo Duplex | 387513 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695549 | Pre-made Cynomolgus/Rhesus macaque TAS2R38/Mamu-T2R38 siRNA oligo Duplex | 695549 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084695 | Pre-made Cat/Feline TAS2R38 siRNA oligo Duplex | 101084695 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100271737 | Pre-made Dog/Canine TAS2R38/CAFA-T2R38 siRNA oligo Duplex | 100271737 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo787789 | Pre-made Bovines/Cattle TAS2R38 siRNA oligo Duplex | 787789 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106783090 | Pre-made Equine/Horse TAS2R38 siRNA oligo Duplex | 106783090 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TAS2R38 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1768-Ab | Human | Anti-Human TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1768-Ab | Rat | Anti-Rat TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1768-Ab | Mouse | Anti-Mouse TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1768-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1768-Ab | Cat/Feline | Anti-Cat/Feline TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1768-Ab | Dog/Canine | Anti-Dog/Canine TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1768-Ab | Bovines/Cattle | Anti-Bovines/Cattle TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1768-Ab | Equine/Horse | Anti-Equine/Horse TAS2R38 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
TAS2R38 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1768-Ag | Human | Human TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1768-Ag | Rat | Rat TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1768-Ag | Mouse | Mouse TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1768-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1768-Ag | Cat/Feline | Cat/Feline TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1768-Ag | Dog/Canine | Dog/Canine TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1768-Ag | Bovines/Cattle | Bovines/Cattle TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1768-Ag | Equine/Horse | Equine/Horse TAS2R38 VLP (virus-like particle) | HEK293 | Products Developing |