Explore STEAP4 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2011]
| Target ID |
GM-MP1715
|
| Target Name |
STEAP4
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
79689
|
| Gene ID |
100059718 (Equus caballus), 101101204 (Felis catus), 117167 (Mus musculus), 482287 (Canis lupus familiaris) 499991 (Rattus norvegicus), 538861 (Bos taurus), 705096 (Macaca mulatta), 79689 (Homo sapiens)
|
| Target Alternative Names |
1110021O17Rik,Metalloreductase STEAP4,STAMP2,STEAP4,SchLAH,Six-transmembrane epithelial antigen of prostate 4,SixTransMembrane protein of prostate 2,Steap4,TIARP,TNFAIP9,Tiarp,Tnfaip9,Tumor necrosis factor,alpha-induced protein 9
|
| Uniprot Accession |
Q923B6,Q4V8K1,Q687X5
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Prostate Cancer
|
| Gene Ensembl |
ENSECAG00000018828, ENSMUSG00000012428, ENSCAFG00845010934, ENSBTAG00000002340, ENSMMUG00000022697, ENSG00000127954
|
Pre-made viral vector of STEAP4 cDNA Clones/ORF Plasmid
STEAP4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79689 | Pre-made Human STEAP4/TIARP/STAMP2 siRNA oligo Duplex | 79689 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo499991 | Pre-made Rat Steap4 siRNA oligo Duplex | 499991 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117167 | Pre-made Mouse Steap4/Tiarp/Tnfaip9 siRNA oligo Duplex | 117167 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705096 | Pre-made Cynomolgus/Rhesus macaque STEAP4 siRNA oligo Duplex | 705096 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101204 | Pre-made Cat/Feline STEAP4 siRNA oligo Duplex | 101101204 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482287 | Pre-made Dog/Canine STEAP4 siRNA oligo Duplex | 482287 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538861 | Pre-made Bovines/Cattle STEAP4 siRNA oligo Duplex | 538861 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059718 | Pre-made Equine/Horse STEAP4 siRNA oligo Duplex | 100059718 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
STEAP4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1715-Ab | Human | Anti-Human STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1715-Ab | Rat | Anti-Rat STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1715-Ab | Mouse | Anti-Mouse STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1715-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1715-Ab | Cat/Feline | Anti-Cat/Feline STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1715-Ab | Dog/Canine | Anti-Dog/Canine STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1715-Ab | Bovines/Cattle | Anti-Bovines/Cattle STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1715-Ab | Equine/Horse | Anti-Equine/Horse STEAP4 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
STEAP4 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1715-Ag | Human | Human STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1715-Ag | Rat | Rat STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1715-Ag | Mouse | Mouse STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1715-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1715-Ag | Cat/Feline | Cat/Feline STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1715-Ag | Dog/Canine | Dog/Canine STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1715-Ag | Bovines/Cattle | Bovines/Cattle STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1715-Ag | Equine/Horse | Equine/Horse STEAP4 VLP (virus-like particle) | HEK293 | Products Developing |