Explore Sortilin/SORT1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
| Target ID |
GM-MP1696
|
| Target Name |
Sortilin/SORT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6272
|
| Gene ID |
100061385 (Equus caballus), 101090199 (Felis catus), 20661 (Mus musculus), 479915 (Canis lupus familiaris)
511591 (Bos taurus), 6272 (Homo sapiens), 698310 (Macaca mulatta), 83576 (Rattus norvegicus)
|
| Target Alternative Names |
SORT1,Sort1,Ntr3,Ntsr3,2900053A11Rik,NT3,Gp95,NTR3,LDLCQ6,Nt3,Nts3
|
| Uniprot Accession |
Q6PHU5,Q99523,O54861
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
|
| Disease from KEGG |
Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism
|
| Gene Ensembl |
ENSECAG00000015853, ENSMUSG00000068747, ENSCAFG00845002996, ENSBTAG00000008849, ENSG00000134243, ENSMMUG00000005812
|
| Target Classification |
|
Sortilin/SORT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6272 | Pre-made Human SORT1/NT3/Gp95 siRNA oligo Duplex | 6272 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83576 | Pre-made Rat Sort1/Nt3/Nts3 siRNA oligo Duplex | 83576 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20661 | Pre-made Mouse Sort1/Ntr3/Ntsr3 siRNA oligo Duplex | 20661 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698310 | Pre-made Cynomolgus/Rhesus macaque SORT1 siRNA oligo Duplex | 698310 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090199 | Pre-made Cat/Feline SORT1 siRNA oligo Duplex | 101090199 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479915 | Pre-made Dog/Canine SORT1 siRNA oligo Duplex | 479915 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511591 | Pre-made Bovines/Cattle SORT1 siRNA oligo Duplex | 511591 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061385 | Pre-made Equine/Horse SORT1 siRNA oligo Duplex | 100061385 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Sortilin/SORT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1696-Ab | Human | Anti-Human Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-MP1696-Ab | Rat | Anti-Rat Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-MP1696-Ab | Mouse | Anti-Mouse Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-MP1696-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-MP1696-Ab | Cat/Feline | Anti-Cat/Feline Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-MP1696-Ab | Dog/Canine | Anti-Dog/Canine Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-MP1696-Ab | Bovines/Cattle | Anti-Bovines/Cattle Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-MP1696-Ab | Equine/Horse | Anti-Equine/Horse Sortilin/SORT1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Sortilin/SORT1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1696-Ag | Human | Human Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1696-Ag | Rat | Rat Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1696-Ag | Mouse | Mouse Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1696-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1696-Ag | Cat/Feline | Cat/Feline Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1696-Ag | Dog/Canine | Dog/Canine Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1696-Ag | Bovines/Cattle | Bovines/Cattle Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1696-Ag | Equine/Horse | Equine/Horse Sortilin/SORT1 VLP (virus-like particle) | HEK293 | Products Developing |
