Explore ASM/SMPD1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
| Target ID |
GM-MP1691
|
| Target Name |
ASM/SMPD1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6609
|
| Gene ID |
100069949 (Equus caballus), 101099497 (Felis catus), 20597 (Mus musculus), 308909 (Rattus norvegicus)
485334 (Canis lupus familiaris), 505097 (Bos taurus), 6609 (Homo sapiens), 711248 (Macaca mulatta)
|
| Target Alternative Names |
A-SMase,ASM,ASMASE,Acid sphingomyelinase (aSMase),NPD,SMPD1,Smpd1,Sphingomyelin phosphodiesterase,Zn-SMase,aSMase
|
| Uniprot Accession |
Q04519,Q0VD19,P17405
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, Sphingolipid signaling pathway, Lysosome, Sphingolipid metabolism
|
| Gene Ensembl |
ENSMUSG00000037049, ENSCAFG00845007383, ENSBTAG00000015628, ENSG00000166311, ENSMMUG00000007717
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ASM/SMPD1 cDNA Clones/ORF Plasmid
ASM/SMPD1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6609 | Pre-made Human SMPD1/ASM/NPD siRNA oligo Duplex | 6609 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308909 | Pre-made Rat Smpd1 siRNA oligo Duplex | 308909 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20597 | Pre-made Mouse Smpd1/ASM/aSMase siRNA oligo Duplex | 20597 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711248 | Pre-made Cynomolgus/Rhesus macaque SMPD1 siRNA oligo Duplex | 711248 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099497 | Pre-made Cat/Feline SMPD1 siRNA oligo Duplex | 101099497 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485334 | Pre-made Dog/Canine SMPD1 siRNA oligo Duplex | 485334 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505097 | Pre-made Bovines/Cattle SMPD1/ASM siRNA oligo Duplex | 505097 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069949 | Pre-made Equine/Horse SMPD1 siRNA oligo Duplex | 100069949 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ASM/SMPD1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1691-Ab | Human | Anti-Human ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1691-Ab | Rat | Anti-Rat ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1691-Ab | Mouse | Anti-Mouse ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1691-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1691-Ab | Cat/Feline | Anti-Cat/Feline ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1691-Ab | Dog/Canine | Anti-Dog/Canine ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1691-Ab | Bovines/Cattle | Anti-Bovines/Cattle ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1691-Ab | Equine/Horse | Anti-Equine/Horse ASM/SMPD1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ASM/SMPD1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1691-Ag | Human | Human ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1691-Ag | Rat | Rat ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1691-Ag | Mouse | Mouse ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1691-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1691-Ag | Cat/Feline | Cat/Feline ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1691-Ag | Dog/Canine | Dog/Canine ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1691-Ag | Bovines/Cattle | Bovines/Cattle ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1691-Ag | Equine/Horse | Equine/Horse ASM/SMPD1 VLP (virus-like particle) | HEK293 | Products Developing |
