Explore SLC6A19 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a system B(0) transmembrane protein that actively transports most neutral amino acids across the apical membrane of epithelial cells. Mutations in this gene may result in Hartnup disorder, an inherited disease with symptoms such as pellagra, cerebellar ataxia, and psychosis. The expression and function of B0AT1 (SLC6A19) in intestinal cells depends on the presence of the accessory protein angiotensin-converting enzyme 2 (ACE2) which, among other functions, acts as a chaperone for membrane trafficking of B0AT1. The ACE2 is also the cellular receptor for severe acute respiratory syndrome-coronavirus (SARS-CoV) and for SARS-CoV-2 that is causing the coronavirus 2019 (COVID-19) pandemic [provided by RefSeq, Jul 2020]
| Target ID |
GM-MP1657
|
| Target Name |
SLC6A19
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
340024
|
| Gene ID |
100069470 (Equus caballus), 100337416 (Bos taurus), 100424683 (Macaca mulatta), 100683912 (Canis lupus familiaris)
123380628 (Felis catus), 340024 (Homo sapiens), 664630 (Rattus norvegicus), 74338 (Mus musculus)
|
| Target Alternative Names |
4632401C08Rik,B0AT1,B0at1,B<0>AT1,HND,SLC6A19,Slc6a19,Sodium-dependent neutral amino acid transporter B(0)AT1,Solute carrier family 6 member 19,System B(0) neutral amino acid transporter AT1
|
| Uniprot Accession |
Q695T7,Q2A865,Q9D687
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Protein digestion and absorption, Mineral absorption
|
| Gene Ensembl |
ENSECAG00000015357, ENSBTAG00000045695, ENSMMUG00000010935, ENSCAFG00845026397, ENSG00000174358, ENSMUSG00000021565
|
Pre-made viral vector of SLC6A19 cDNA Clones/ORF Plasmid
SLC6A19 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo340024 | Pre-made Human SLC6A19/HND/B0AT1 siRNA oligo Duplex | 340024 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo664630 | Pre-made Rat Slc6a19/B0at1 siRNA oligo Duplex | 664630 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74338 | Pre-made Mouse Slc6a19/B<0>AT1/4632401C08Rik siRNA oligo Duplex | 74338 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100424683 | Pre-made Cynomolgus/Rhesus macaque SLC6A19 siRNA oligo Duplex | 100424683 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo123380628 | Pre-made Cat/Feline SLC6A19 siRNA oligo Duplex | 123380628 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100683912 | Pre-made Dog/Canine SLC6A19 siRNA oligo Duplex | 100683912 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100337416 | Pre-made Bovines/Cattle SLC6A19 siRNA oligo Duplex | 100337416 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069470 | Pre-made Equine/Horse SLC6A19 siRNA oligo Duplex | 100069470 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SLC6A19 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1657-Ab | Human | Anti-Human SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1657-Ab | Rat | Anti-Rat SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1657-Ab | Mouse | Anti-Mouse SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1657-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1657-Ab | Cat/Feline | Anti-Cat/Feline SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1657-Ab | Dog/Canine | Anti-Dog/Canine SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1657-Ab | Bovines/Cattle | Anti-Bovines/Cattle SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1657-Ab | Equine/Horse | Anti-Equine/Horse SLC6A19 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SLC6A19 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1657-Ag | Human | Human SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1657-Ag | Rat | Rat SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1657-Ag | Mouse | Mouse SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1657-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1657-Ag | Cat/Feline | Cat/Feline SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1657-Ag | Dog/Canine | Dog/Canine SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1657-Ag | Bovines/Cattle | Bovines/Cattle SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1657-Ag | Equine/Horse | Equine/Horse SLC6A19 VLP (virus-like particle) | HEK293 | Products Developing |
