Explore ZIP8/SLC39A8 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]
| Target ID |
GM-MP1619
|
| Target Name |
ZIP8/SLC39A8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
64116
|
| Gene ID |
100067821 (Equus caballus), 101096887 (Felis catus), 295455 (Rattus norvegicus), 478494 (Canis lupus familiaris)
508193 (Bos taurus), 64116 (Homo sapiens), 67547 (Mus musculus), 710142 (Macaca mulatta)
|
| Target Alternative Names |
4933419D20Rik,BCG-induced integral membrane protein in monocyte clone 103 protein,BIGM103,CDG2N,LIV-1 subfamily of ZIP zinc transporter 6 (LZT-Hs6),LZT-Hs6,Metal cation symporter ZIP8,PP3105,SLC39A8,Slc39a8,Solute carrier family 39 member 8,ZIP-8,ZIP8,Zip8,Zrt- and Irt-like protein 8 (ZIP-8)
|
| Uniprot Accession |
Q5FVQ0,Q9C0K1,Q91W10
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Ferroptosis, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000025010, ENSBTAG00000005668, ENSG00000138821, ENSMUSG00000053897, ENSMMUG00000016880
|
Pre-made viral vector of ZIP8/SLC39A8 cDNA Clones/ORF Plasmid
ZIP8/SLC39A8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo64116 | Pre-made Human SLC39A8/ZIP8/CDG2N siRNA oligo Duplex | 64116 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295455 | Pre-made Rat Slc39a8 siRNA oligo Duplex | 295455 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo67547 | Pre-made Mouse Slc39a8/Zip8/ZIP-8 siRNA oligo Duplex | 67547 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710142 | Pre-made Cynomolgus/Rhesus macaque SLC39A8 siRNA oligo Duplex | 710142 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096887 | Pre-made Cat/Feline SLC39A8 siRNA oligo Duplex | 101096887 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478494 | Pre-made Dog/Canine SLC39A8 siRNA oligo Duplex | 478494 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508193 | Pre-made Bovines/Cattle SLC39A8 siRNA oligo Duplex | 508193 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067821 | Pre-made Equine/Horse SLC39A8 siRNA oligo Duplex | 100067821 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ZIP8/SLC39A8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1619-Ab | Human | Anti-Human ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1619-Ab | Rat | Anti-Rat ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1619-Ab | Mouse | Anti-Mouse ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1619-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1619-Ab | Cat/Feline | Anti-Cat/Feline ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1619-Ab | Dog/Canine | Anti-Dog/Canine ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1619-Ab | Bovines/Cattle | Anti-Bovines/Cattle ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1619-Ab | Equine/Horse | Anti-Equine/Horse ZIP8/SLC39A8 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ZIP8/SLC39A8 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1619-Ag | Human | Human ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1619-Ag | Rat | Rat ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1619-Ag | Mouse | Mouse ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1619-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1619-Ag | Cat/Feline | Cat/Feline ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1619-Ag | Dog/Canine | Dog/Canine ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1619-Ag | Bovines/Cattle | Bovines/Cattle ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1619-Ag | Equine/Horse | Equine/Horse ZIP8/SLC39A8 VLP (virus-like particle) | HEK293 | Products Developing |
