Explore OCTN2/SLC22A5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]
| Target ID |
GM-MP1564
|
| Target Name |
OCTN2/SLC22A5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6584
|
| Gene ID |
100072871 (Equus caballus), 20520 (Mus musculus), 29726 (Rattus norvegicus), 541266 (Bos taurus) 608146 (Canis lupus familiaris), 6584 (Homo sapiens), 707590 (Macaca mulatta)
|
| Target Alternative Names |
CDSP,CT1,High-affinity sodium-dependent carnitine cotransporter,Lstpl,OCTN2,Octn2,Organic cation/carnitine transporter 2,SLC22A5,Slc22a5,Solute carrier family 22 member 5,UST2r,jvs
|
| Uniprot Accession |
Q9Z0E8,O70594,O76082
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Choline metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000021721, ENSMUSG00000018900, ENSBTAG00000000668, ENSCAFG00845010298, ENSG00000197375, ENSMMUG00000007087
|
Pre-made viral vector of OCTN2/SLC22A5 cDNA Clones/ORF Plasmid
OCTN2/SLC22A5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6584 | Pre-made Human SLC22A5/CDSP/OCTN2 siRNA oligo Duplex | 6584 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29726 | Pre-made Rat Slc22a5/CT1/OCTN2 siRNA oligo Duplex | 29726 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20520 | Pre-made Mouse Slc22a5/jvs/Lstpl siRNA oligo Duplex | 20520 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707590 | Pre-made Cynomolgus/Rhesus macaque SLC22A5 siRNA oligo Duplex | 707590 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608146 | Pre-made Dog/Canine SLC22A5 siRNA oligo Duplex | 608146 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541266 | Pre-made Bovines/Cattle SLC22A5 siRNA oligo Duplex | 541266 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072871 | Pre-made Equine/Horse SLC22A5 siRNA oligo Duplex | 100072871 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OCTN2/SLC22A5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1564-Ab | Human | Anti-Human OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1564-Ab | Rat | Anti-Rat OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1564-Ab | Mouse | Anti-Mouse OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1564-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1564-Ab | Dog/Canine | Anti-Dog/Canine OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1564-Ab | Bovines/Cattle | Anti-Bovines/Cattle OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1564-Ab | Equine/Horse | Anti-Equine/Horse OCTN2/SLC22A5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
OCTN2/SLC22A5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1564-Ag | Human | Human OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1564-Ag | Rat | Rat OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1564-Ag | Mouse | Mouse OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1564-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1564-Ag | Dog/Canine | Dog/Canine OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1564-Ag | Bovines/Cattle | Bovines/Cattle OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1564-Ag | Equine/Horse | Equine/Horse OCTN2/SLC22A5 VLP (virus-like particle) | HEK293 | Products Developing |