Explore SIRP Beta 1/SIRPB1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
| Target ID |
GM-MP1527
|
| Target Name |
SIRP Beta 1/SIRPB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10326
|
| Gene ID |
100067561 (Equus caballus), 10326 (Homo sapiens)
|
| Target Alternative Names |
CD172b,SIRP Beta 1,SIRP-BETA-1,SIRPB1
|
| Uniprot Accession |
O00241,Q5TFQ8
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Osteoclast differentiation
|
| Gene Ensembl |
ENSG00000101307
|
SIRP Beta 1/SIRPB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10326 | Pre-made Human SIRPB1/CD172b/SIRP-BETA-1 siRNA oligo Duplex | 10326 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067561 | Pre-made Equine/Horse SIRPB1 siRNA oligo Duplex | 100067561 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SIRP Beta 1/SIRPB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1527-Ab | Human | Anti-Human SIRP Beta 1/SIRPB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1527-Ab | Equine/Horse | Anti-Equine/Horse SIRP Beta 1/SIRPB1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SIRP Beta 1/SIRPB1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1527-Ag | Human | Human SIRP Beta 1/SIRPB1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1527-Ag | Equine/Horse | Equine/Horse SIRP Beta 1/SIRPB1 VLP (virus-like particle) | HEK293 | Products Developing |
