Explore SIGLEC5/CD170 gene products and cross-species
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]
| Target ID |
GM-MP1522
|
| Target Name |
SIGLEC5/CD170
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8778
|
| Gene ID |
101094223 (Felis catus), 719730 (Macaca mulatta), 8778 (Homo sapiens)
|
| Target Alternative Names |
CD170,CD33 antigen-like 2,CD33L2,OB-BP2,OB-binding protein 2),OBBP2,Obesity-binding protein 2 (OB-BP2,SIGLEC-5,SIGLEC5,Sialic acid-binding Ig-like lectin 5,Siglec-5
|
| Uniprot Accession |
O15389
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSMMUG00000012761, ENSG00000268500
|
SIGLEC5/CD170 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8778 | Pre-made Human SIGLEC5/CD170/OBBP2 siRNA oligo Duplex | 8778 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719730 | Pre-made Cynomolgus/Rhesus macaque SIGLEC5 siRNA oligo Duplex | 719730 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094223 | Pre-made Cat/Feline SIGLEC5 siRNA oligo Duplex | 101094223 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
SIGLEC5/CD170 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1522-Ab | Human | Anti-Human SIGLEC5/CD170 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1522-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SIGLEC5/CD170 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1522-Ab | Cat/Feline | Anti-Cat/Feline SIGLEC5/CD170 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SIGLEC5/CD170 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1522-Ag | Human | Human SIGLEC5/CD170 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1522-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SIGLEC5/CD170 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1522-Ag | Cat/Feline | Cat/Feline SIGLEC5/CD170 VLP (virus-like particle) | HEK293 | Products Developing |
