Explore CD169/SIGLEC1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. The protein plays an important role in multiple human diseases and bacterial and viral infections has been shown to enhance SARS-CoV-2 infection. [provided by RefSeq, Dec 2021]
| Target ID |
GM-MP1518
|
| Target Name |
CD169/SIGLEC1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6614
|
| Gene ID |
100066351 (Equus caballus), 101093264 (Felis catus), 20612 (Mus musculus), 311426 (Rattus norvegicus)
485794 (Canis lupus familiaris), 539759 (Bos taurus), 6614 (Homo sapiens), 717470 (Macaca mulatta)
|
| Target Alternative Names |
CD169,Cd169,SIGLEC-1,SIGLEC1,SN,Sialic acid-binding Ig-like lectin 1 (Siglec-1),Sialoadhesin,Siglec-1,Siglec1,Sn
|
| Uniprot Accession |
Q62230,Q9BZZ2
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000014218, ENSMUSG00000027322, ENSCAFG00845014296, ENSBTAG00000013167, ENSG00000088827, ENSMMUG00000022070
|
CD169/SIGLEC1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6614 | Pre-made Human SIGLEC1/SN/CD169 siRNA oligo Duplex | 6614 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo311426 | Pre-made Rat Siglec1/Sn siRNA oligo Duplex | 311426 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20612 | Pre-made Mouse Siglec1/Sn/Cd169 siRNA oligo Duplex | 20612 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717470 | Pre-made Cynomolgus/Rhesus macaque SIGLEC1 siRNA oligo Duplex | 717470 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093264 | Pre-made Cat/Feline SIGLEC1 siRNA oligo Duplex | 101093264 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485794 | Pre-made Dog/Canine SIGLEC1 siRNA oligo Duplex | 485794 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539759 | Pre-made Bovines/Cattle SIGLEC1 siRNA oligo Duplex | 539759 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066351 | Pre-made Equine/Horse SIGLEC1 siRNA oligo Duplex | 100066351 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD169/SIGLEC1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1518-Ab | Human | Anti-Human CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1518-Ab | Rat | Anti-Rat CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1518-Ab | Mouse | Anti-Mouse CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1518-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1518-Ab | Cat/Feline | Anti-Cat/Feline CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1518-Ab | Dog/Canine | Anti-Dog/Canine CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1518-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1518-Ab | Equine/Horse | Anti-Equine/Horse CD169/SIGLEC1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD169/SIGLEC1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1518-Ag | Human | Human CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1518-Ag | Rat | Rat CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1518-Ag | Mouse | Mouse CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1518-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1518-Ag | Cat/Feline | Cat/Feline CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1518-Ag | Dog/Canine | Dog/Canine CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1518-Ag | Bovines/Cattle | Bovines/Cattle CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1518-Ag | Equine/Horse | Equine/Horse CD169/SIGLEC1 VLP (virus-like particle) | HEK293 | Products Developing |
