Explore SFRP1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq, Sep 2009]
| Target ID |
GM-MP1510
|
| Target Name |
SFRP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6422
|
| Gene ID |
100055845 (Equus caballus), 101083585 (Felis catus), 20377 (Mus musculus), 282068 (Bos taurus)
482844 (Canis lupus familiaris), 6422 (Homo sapiens), 702876 (Macaca mulatta), 84402 (Rattus norvegicus)
|
| Target Alternative Names |
2210415K03Rik,FRP,FRP-1,FRP1,FrzA,SARP2,SFRP1,Secreted apoptosis-related protein 2 (SARP-2),Secreted frizzled-related protein 1,Sfrp1,sFRP-1
|
| Uniprot Accession |
Q8C4U3,O19116,Q8N474,Q9R168
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
Wnt signaling pathway
|
| Gene Ensembl |
ENSECAG00000021358, ENSMUSG00000031548, ENSCAFG00845008758, ENSG00000104332, ENSMMUG00000019082
|
Pre-made viral vector of SFRP1 cDNA Clones/ORF Plasmid
SFRP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6422 | Pre-made Human SFRP1/FRP/FRP1 siRNA oligo Duplex | 6422 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84402 | Pre-made Rat Sfrp1/sFRP-1 siRNA oligo Duplex | 84402 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20377 | Pre-made Mouse Sfrp1/sFRP-1/2210415K03Rik siRNA oligo Duplex | 20377 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702876 | Pre-made Cynomolgus/Rhesus macaque SFRP1 siRNA oligo Duplex | 702876 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083585 | Pre-made Cat/Feline SFRP1 siRNA oligo Duplex | 101083585 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482844 | Pre-made Dog/Canine SFRP1/FrzA siRNA oligo Duplex | 482844 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282068 | Pre-made Bovines/Cattle SFRP1 siRNA oligo Duplex | 282068 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055845 | Pre-made Equine/Horse SFRP1 siRNA oligo Duplex | 100055845 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SFRP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1510-Ab | Human | Anti-Human SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1510-Ab | Rat | Anti-Rat SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1510-Ab | Mouse | Anti-Mouse SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1510-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1510-Ab | Cat/Feline | Anti-Cat/Feline SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1510-Ab | Dog/Canine | Anti-Dog/Canine SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1510-Ab | Bovines/Cattle | Anti-Bovines/Cattle SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1510-Ab | Equine/Horse | Anti-Equine/Horse SFRP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SFRP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1510-Ag | Human | Human SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1510-Ag | Rat | Rat SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1510-Ag | Mouse | Mouse SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1510-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1510-Ag | Cat/Feline | Cat/Feline SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1510-Ag | Dog/Canine | Dog/Canine SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1510-Ag | Bovines/Cattle | Bovines/Cattle SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1510-Ag | Equine/Horse | Equine/Horse SFRP1 VLP (virus-like particle) | HEK293 | Products Developing |
