Explore RYR2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP1478
|
| Target Name |
RYR2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6262
|
| Gene ID |
100057437 (Equus caballus), 101084482 (Felis catus), 20191 (Mus musculus), 403615 (Canis lupus familiaris)
537376 (Bos taurus), 6262 (Homo sapiens), 689560 (Rattus norvegicus), 717179 (Macaca mulatta)
|
| Target Alternative Names |
9330127I20Rik,ARVC2,ARVD2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,RYR-2,RYR2,RyR,RyR2,Ryanodine receptor 2,Ryr2,Type 2 ryanodine receptor,VACRDS,VTSIP,hRYR-2
|
| Uniprot Accession |
E9Q401,Q92736,B0LPN4
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Calcium signaling pathway, cAMP signaling pathway, Adrenergic signaling in cardiomyocytes, Circadian entrainment, Insulin secretion, Oxytocin signaling pathway, Pancreatic secretion, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000006795, ENSMUSG00000021313, ENSCAFG00845002388, ENSBTAG00000022886, ENSG00000198626, ENSMMUG00000001060
|
RYR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6262 | Pre-made Human RYR2/RyR/ARVC2 siRNA oligo Duplex | 6262 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo689560 | Pre-made Rat Ryr2/RyR/RYR-2 siRNA oligo Duplex | 689560 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20191 | Pre-made Mouse Ryr2/RYR-2/9330127I20Rik siRNA oligo Duplex | 20191 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717179 | Pre-made Cynomolgus/Rhesus macaque RYR2 siRNA oligo Duplex | 717179 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084482 | Pre-made Cat/Feline RYR2 siRNA oligo Duplex | 101084482 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403615 | Pre-made Dog/Canine RYR2 siRNA oligo Duplex | 403615 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo537376 | Pre-made Bovines/Cattle RYR2 siRNA oligo Duplex | 537376 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057437 | Pre-made Equine/Horse RYR2 siRNA oligo Duplex | 100057437 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RYR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1478-Ab | Human | Anti-Human RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1478-Ab | Rat | Anti-Rat RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1478-Ab | Mouse | Anti-Mouse RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1478-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1478-Ab | Cat/Feline | Anti-Cat/Feline RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1478-Ab | Dog/Canine | Anti-Dog/Canine RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1478-Ab | Bovines/Cattle | Anti-Bovines/Cattle RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1478-Ab | Equine/Horse | Anti-Equine/Horse RYR2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
RYR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1478-Ag | Human | Human RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1478-Ag | Rat | Rat RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1478-Ag | Mouse | Mouse RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1478-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1478-Ag | Cat/Feline | Cat/Feline RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1478-Ag | Dog/Canine | Dog/Canine RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1478-Ag | Bovines/Cattle | Bovines/Cattle RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1478-Ag | Equine/Horse | Equine/Horse RYR2 VLP (virus-like particle) | HEK293 | Products Developing |
