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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
| Target ID |
GM-MP1451
|
| Target Name |
RAMP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10267
|
| Gene ID |
100066550 (Equus caballus), 101092133 (Felis catus), 10267 (Homo sapiens), 51801 (Mus musculus) 574329 (Macaca mulatta), 58965 (Rattus norvegicus), 607163 (Canis lupus familiaris), 617017 (Bos taurus)
|
| Target Alternative Names |
9130218E19Rik,Calcitonin-receptor-like receptor activity-modifying protein 1 (CRLR activity-modifying protein 1),RAMP1,Ramp1,Receptor activity-modifying protein 1
|
| Uniprot Accession |
O60894,Q9WTJ5,Q9JJ74
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Vascular smooth muscle contraction
|
| Gene Ensembl |
ENSECAG00000009250, ENSG00000132329, ENSMUSG00000034353, ENSMMUG00000052071, ENSCAFG00845029374, ENSBTAG00000011534
|
Pre-made viral vector of RAMP1 cDNA Clones/ORF Plasmid
RAMP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10267 | Pre-made Human RAMP1 siRNA oligo Duplex | 10267 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58965 | Pre-made Rat Ramp1 siRNA oligo Duplex | 58965 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo51801 | Pre-made Mouse Ramp1/9130218E19Rik siRNA oligo Duplex | 51801 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574329 | Pre-made Cynomolgus/Rhesus macaque RAMP1 siRNA oligo Duplex | 574329 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092133 | Pre-made Cat/Feline RAMP1 siRNA oligo Duplex | 101092133 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607163 | Pre-made Dog/Canine RAMP1 siRNA oligo Duplex | 607163 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617017 | Pre-made Bovines/Cattle RAMP1 siRNA oligo Duplex | 617017 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066550 | Pre-made Equine/Horse RAMP1 siRNA oligo Duplex | 100066550 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RAMP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1451-Ab | Human | Anti-Human RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1451-Ab | Rat | Anti-Rat RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1451-Ab | Mouse | Anti-Mouse RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1451-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1451-Ab | Cat/Feline | Anti-Cat/Feline RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1451-Ab | Dog/Canine | Anti-Dog/Canine RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1451-Ab | Bovines/Cattle | Anti-Bovines/Cattle RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1451-Ab | Equine/Horse | Anti-Equine/Horse RAMP1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
RAMP1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1451-Ag | Human | Human RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1451-Ag | Rat | Rat RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1451-Ag | Mouse | Mouse RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1451-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1451-Ag | Cat/Feline | Cat/Feline RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1451-Ag | Dog/Canine | Dog/Canine RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1451-Ag | Bovines/Cattle | Bovines/Cattle RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1451-Ag | Equine/Horse | Equine/Horse RAMP1 VLP (virus-like particle) | HEK293 | Products Developing |