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Target
sublocation: Transmembrane Protein.
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]
| Target ID |
GM-MP1447
|
| Target Name |
RAET1E
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
135250
|
| Gene ID |
135250 (Homo sapiens)
|
| Target Alternative Names |
LETAL,Lymphocyte effector toxicity activation ligand,N2DL-4,NKG2D ligand 4 (N2DL-4,NKG2DL4,NKG2DL4),RAE-1-like transcript 4,RAET1E,RAET1E2,RL-4,Retinoic acid early transcript 1E,UL16-binding protein 4,ULBP4,bA350J20.7
|
| Uniprot Accession |
Q8TD07
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity
|
| Gene Ensembl |
ENSG00000164520
|
Pre-made viral vector of RAET1E cDNA Clones/ORF Plasmid
RAET1E siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo135250 | Pre-made Human RAET1E/RL-4/LETAL siRNA oligo Duplex | 135250 | Human | In-vitro grade; in-vivo grade | Detail |
RAET1E antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1447-Ab | Human | Anti-Human RAET1E monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
RAET1E VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1447-Ag | Human | Human RAET1E VLP (virus-like particle) | HEK293 | Products Developing |