Explore Nectin-1/PVRL1/NECTIN1/CD111 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
| Target ID |
GM-MP1439
|
| Target Name |
Nectin-1/PVRL1/NECTIN1/CD111
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5818
|
| Gene ID |
101098252 (Felis catus), 192183 (Rattus norvegicus), 489363 (Canis lupus familiaris), 533492 (Bos taurus)
5818 (Homo sapiens), 58235 (Mus musculus), 710072 (Macaca mulatta)
|
| Target Alternative Names |
CD111,CLPED1,Cd111,ED4,HIgR,HV1S,HVEC,Herpes virus entry mediator C (Herpesvirus entry mediator C,Herpesvirus Ig-like receptor (HIgR),HveC,HveC),NECTIN1,Nectin cell adhesion molecule 1,Nectin-1,Nectin1,OFC7,PRR,PRR1,PVRL1,PVRR,PVRR1,Poliovirus receptor-related protein 1,Pvrl1,SK-12,nectin-1,prr1
|
| Uniprot Accession |
Q15223,Q9JKF6
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Cell adhesion molecules, Adherens junction
|
| Gene Ensembl |
ENSCAFG00845014377, ENSBTAG00000015939, ENSG00000110400, ENSMUSG00000032012, ENSMMUG00000008274
|
| Target Classification |
|
Nectin-1/PVRL1/NECTIN1/CD111 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5818 | Pre-made Human NECTIN1/ED4/PRR siRNA oligo Duplex | 5818 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo192183 | Pre-made Rat Nectin1/HveC/Pvrl1 siRNA oligo Duplex | 192183 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58235 | Pre-made Mouse Nectin1/PRR/HIgR siRNA oligo Duplex | 58235 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710072 | Pre-made Cynomolgus/Rhesus macaque NECTIN1 siRNA oligo Duplex | 710072 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098252 | Pre-made Cat/Feline NECTIN1 siRNA oligo Duplex | 101098252 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489363 | Pre-made Dog/Canine NECTIN1/prr1 siRNA oligo Duplex | 489363 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533492 | Pre-made Bovines/Cattle NECTIN1/HVEC/prr1 siRNA oligo Duplex | 533492 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
Nectin-1/PVRL1/NECTIN1/CD111 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1439-Ab | Human | Anti-Human Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1439-Ab | Rat | Anti-Rat Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1439-Ab | Mouse | Anti-Mouse Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1439-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1439-Ab | Cat/Feline | Anti-Cat/Feline Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1439-Ab | Dog/Canine | Anti-Dog/Canine Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1439-Ab | Bovines/Cattle | Anti-Bovines/Cattle Nectin-1/PVRL1/NECTIN1/CD111 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1439-Ag | Human | Human Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1439-Ag | Rat | Rat Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1439-Ag | Mouse | Mouse Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1439-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1439-Ag | Cat/Feline | Cat/Feline Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1439-Ag | Dog/Canine | Dog/Canine Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1439-Ag | Bovines/Cattle | Bovines/Cattle Nectin-1/PVRL1/NECTIN1/CD111 VLP (virus-like particle) | HEK293 | Products Developing |
