Explore PTPRU gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Alternatively spliced transcript variants have been reported. [provided by RefSeq, Aug 2010]
| Target ID |
GM-MP1438
|
| Target Name |
PTPRU
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10076
|
| Gene ID |
100070588 (Equus caballus), 10076 (Homo sapiens), 101092380 (Felis catus), 116680 (Rattus norvegicus)
19273 (Mus musculus), 487328 (Canis lupus familiaris), 535675 (Bos taurus), 720393 (Macaca mulatta)
|
| Target Alternative Names |
PTPRU,Ptpru,FMI,PTP,PCP-2,PTP-J,PTPRO,PTPU2,PTP-PI,PTP-RO,PTPPSI,hPTP-J,R-PTP-U,R-PTP-PSI,Pcp2,Ptpf,Ftp-1,Ptprl,PTPlambda,R-PTP-psi,PTP-lambda,RPTPlambda
|
| Uniprot Accession |
Q92729,B1AUH1
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000012344, ENSG00000060656, ENSMUSG00000028909, ENSCAFG00845007699, ENSBTAG00000012848, ENSMMUG00000015661
|
| Target Classification |
|
PTPRU siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10076 | Pre-made Human PTPRU/FMI/PTP siRNA oligo Duplex | 10076 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116680 | Pre-made Rat Ptpru siRNA oligo Duplex | 116680 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19273 | Pre-made Mouse Ptpru/PTP/Pcp2 siRNA oligo Duplex | 19273 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720393 | Pre-made Cynomolgus/Rhesus macaque PTPRU siRNA oligo Duplex | 720393 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092380 | Pre-made Cat/Feline PTPRU siRNA oligo Duplex | 101092380 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487328 | Pre-made Dog/Canine PTPRU siRNA oligo Duplex | 487328 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535675 | Pre-made Bovines/Cattle PTPRU siRNA oligo Duplex | 535675 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070588 | Pre-made Equine/Horse PTPRU siRNA oligo Duplex | 100070588 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTPRU antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1438-Ab | Human | Anti-Human PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1438-Ab | Rat | Anti-Rat PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1438-Ab | Mouse | Anti-Mouse PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1438-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1438-Ab | Cat/Feline | Anti-Cat/Feline PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1438-Ab | Dog/Canine | Anti-Dog/Canine PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1438-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1438-Ab | Equine/Horse | Anti-Equine/Horse PTPRU monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PTPRU VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1438-Ag | Human | Human PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1438-Ag | Rat | Rat PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1438-Ag | Mouse | Mouse PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1438-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1438-Ag | Cat/Feline | Cat/Feline PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1438-Ag | Dog/Canine | Dog/Canine PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1438-Ag | Bovines/Cattle | Bovines/Cattle PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1438-Ag | Equine/Horse | Equine/Horse PTPRU VLP (virus-like particle) | HEK293 | Products Developing |
