Explore PTPRO gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]
| Target ID |
GM-MP1435
|
| Target Name |
PTPRO
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5800
|
| Gene ID |
100064067 (Equus caballus), 101098147 (Felis catus), 19277 (Mus musculus), 486664 (Canis lupus familiaris)
50677 (Rattus norvegicus), 541043 (Bos taurus), 5800 (Homo sapiens), 700811 (Macaca mulatta)
|
| Target Alternative Names |
PTPRO,Ptpro,D28,PTPBK,PTPU2,PTPoc,GLEPP1,PTPROt,PTPphi,Ptpn15,R-PTP-O,RPTP-BK,NPHS6,PTP-OC,PTP-U2,PTPROT
|
| Uniprot Accession |
E9Q612,Q16827
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000015695, ENSMUSG00000030223, ENSCAFG00845020349, ENSBTAG00000006256, ENSG00000151490, ENSMMUG00000032109
|
| Target Classification |
|
PTPRO siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5800 | Pre-made Human PTPRO/NPHS6/PTPU2 siRNA oligo Duplex | 5800 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50677 | Pre-made Rat Ptpro/GLEPP1/RPTP-BK siRNA oligo Duplex | 50677 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19277 | Pre-made Mouse Ptpro/D28/PTPBK siRNA oligo Duplex | 19277 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700811 | Pre-made Cynomolgus/Rhesus macaque PTPRO siRNA oligo Duplex | 700811 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098147 | Pre-made Cat/Feline PTPRO siRNA oligo Duplex | 101098147 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486664 | Pre-made Dog/Canine PTPRO siRNA oligo Duplex | 486664 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo541043 | Pre-made Bovines/Cattle PTPRO siRNA oligo Duplex | 541043 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064067 | Pre-made Equine/Horse PTPRO siRNA oligo Duplex | 100064067 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTPRO antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1435-Ab | Human | Anti-Human PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1435-Ab | Rat | Anti-Rat PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1435-Ab | Mouse | Anti-Mouse PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1435-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1435-Ab | Cat/Feline | Anti-Cat/Feline PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1435-Ab | Dog/Canine | Anti-Dog/Canine PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1435-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1435-Ab | Equine/Horse | Anti-Equine/Horse PTPRO monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PTPRO VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1435-Ag | Human | Human PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1435-Ag | Rat | Rat PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1435-Ag | Mouse | Mouse PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1435-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1435-Ag | Cat/Feline | Cat/Feline PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1435-Ag | Dog/Canine | Dog/Canine PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1435-Ag | Bovines/Cattle | Bovines/Cattle PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1435-Ag | Equine/Horse | Equine/Horse PTPRO VLP (virus-like particle) | HEK293 | Products Developing |
