Explore PTPRD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]
| Target ID |
GM-MP1428
|
| Target Name |
PTPRD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5789
|
| Gene ID |
100051885 (Equus caballus), 101094634 (Felis catus), 19266 (Mus musculus), 313278 (Rattus norvegicus)
481538 (Canis lupus familiaris), 532751 (Bos taurus), 5789 (Homo sapiens), 714954 (Macaca mulatta)
|
| Target Alternative Names |
1110002J03Rik,3000002J10Rik,B230219D21Rik,HPTP,HPTPD,HPTPDELTA,PTPD,PTPRD,Protein-tyrosine phosphatase delta,Ptprd,R-PTP-delta,RPTPDELTA,Receptor-type tyrosine-protein phosphatase delta
|
| Uniprot Accession |
Q64487,P23468
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000009864, ENSMUSG00000028399, ENSCAFG00845026437, ENSBTAG00000010178, ENSG00000153707, ENSMMUG00000006952
|
| Target Classification |
Tumor-associated antigen (TAA)
|
PTPRD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5789 | Pre-made Human PTPRD/HPTP/PTPD siRNA oligo Duplex | 5789 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo313278 | Pre-made Rat Ptprd siRNA oligo Duplex | 313278 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19266 | Pre-made Mouse Ptprd/R-PTP-delta/1110002J03Rik siRNA oligo Duplex | 19266 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714954 | Pre-made Cynomolgus/Rhesus macaque PTPRD siRNA oligo Duplex | 714954 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094634 | Pre-made Cat/Feline PTPRD siRNA oligo Duplex | 101094634 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481538 | Pre-made Dog/Canine PTPRD siRNA oligo Duplex | 481538 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532751 | Pre-made Bovines/Cattle PTPRD siRNA oligo Duplex | 532751 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051885 | Pre-made Equine/Horse PTPRD siRNA oligo Duplex | 100051885 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTPRD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1428-Ab | Human | Anti-Human PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1428-Ab | Rat | Anti-Rat PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1428-Ab | Mouse | Anti-Mouse PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1428-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1428-Ab | Cat/Feline | Anti-Cat/Feline PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1428-Ab | Dog/Canine | Anti-Dog/Canine PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1428-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1428-Ab | Equine/Horse | Anti-Equine/Horse PTPRD monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PTPRD VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1428-Ag | Human | Human PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1428-Ag | Rat | Rat PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1428-Ag | Mouse | Mouse PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1428-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1428-Ag | Cat/Feline | Cat/Feline PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1428-Ag | Dog/Canine | Dog/Canine PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1428-Ag | Bovines/Cattle | Bovines/Cattle PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1428-Ag | Equine/Horse | Equine/Horse PTPRD VLP (virus-like particle) | HEK293 | Products Developing |
