PSAP Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PSAP gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

Target ID GM-MP1417
Target Name PSAP
Gene Group ldentifer
(Target Gene ID in Homo species)
5660
Gene ID 100063520 (Equus caballus), 101080406 (Felis catus), 19156 (Mus musculus), 25524 (Rattus norvegicus)
281433 (Bos taurus), 479240 (Canis lupus familiaris), 5660 (Homo sapiens), 709510 (Macaca mulatta)
Target Alternative Names GLBA,PARK24,PSAP,PSAPD,Proactivator polypeptide,Prosaposin,Psap,SAP1,SAP2,SGP-1,SGP1A
Uniprot Accession Q61207,P10960,P26779,P07602
Protein Sub-location Transmembrane Protein
Disease Ovary Cancer, Malignant neoplasm of bladder
Disease from KEGG Lysosome, Sphingolipid metabolism
Gene Ensembl ENSECAG00000021672, ENSMUSG00000004207, ENSBTAG00000021499, ENSCAFG00845004604, ENSG00000197746, ENSMMUG00000012969


Pre-made viral vector of PSAP cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP003316Human PSAP/GLBA/SAP1 Lentivirus plasmidNM_0027785660HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP003316Human PSAP/GLBA/SAP1 Lentivirus particleNM_0027785660HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAD001480Rat Psap/SGP-1/SGP1A Adenovirus plasmidNM_001190236.125524RatAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC001614Rat Psap/SGP-1/SGP1A Mammalian (Non-Viral Vector) plasmidNM_001190236.125524RatMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAD001480Rat Psap/SGP-1/SGP1A Adenovirus particleNM_001190236.125524RatAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMLPm003423Mouse Psap/AI037048/SGP-1 Lentivirus plasmidNM_001146120.119156MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm003423Mouse Psap/AI037048/SGP-1 Lentivirus particleNM_001146120.119156MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


PSAP siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5660Pre-made Human PSAP/GLBA/SAP1 siRNA oligo Duplex5660HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo25524Pre-made Rat Psap/SGP-1/SGP1A siRNA oligo Duplex25524RatIn-vitro grade; in-vivo gradeDetail
pGMoligo19156Pre-made Mouse Psap/SGP-1 siRNA oligo Duplex19156MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo709510Pre-made Cynomolgus/Rhesus macaque PSAP siRNA oligo Duplex709510Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101080406Pre-made Cat/Feline PSAP siRNA oligo Duplex101080406Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo479240Pre-made Dog/Canine PSAP siRNA oligo Duplex479240Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281433Pre-made Bovines/Cattle PSAP siRNA oligo Duplex281433Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100063520Pre-made Equine/Horse PSAP siRNA oligo Duplex100063520Equine/HorseIn-vitro grade; in-vivo gradeDetail


PSAP antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-MP1417-AbHumanAnti-Human PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-rg-MP1417-AbRatAnti-Rat PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-mg-MP1417-AbMouseAnti-Mouse PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cynog-MP1417-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-felg-MP1417-AbCat/FelineAnti-Cat/Feline PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cang-MP1417-AbDog/CanineAnti-Dog/Canine PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-bovg-MP1417-AbBovines/CattleAnti-Bovines/Cattle PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-equg-MP1417-AbEquine/HorseAnti-Equine/Horse PSAP monoclonal antibodymabFACS/Biofunctional AntibodyDetail


PSAP VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-MP1417-AgHumanHuman PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-MP1417-AgRatRat PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-MP1417-AgMouseMouse PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-MP1417-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-MP1417-AgCat/FelineCat/Feline PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-MP1417-AgDog/CanineDog/Canine PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-MP1417-AgBovines/CattleBovines/Cattle PSAP VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-MP1417-AgEquine/HorseEquine/Horse PSAP VLP (virus-like particle)HEK293Products Developing