Explore PROS1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]
| Target ID |
GM-MP1407
|
| Target Name |
PROS1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5627
|
| Gene ID |
100072912 (Equus caballus), 101085823 (Felis catus), 19128 (Mus musculus), 282006 (Bos taurus)
478529 (Canis lupus familiaris), 5627 (Homo sapiens), 694845 (Macaca mulatta), 81750 (Rattus norvegicus)
|
| Target Alternative Names |
PROS,PROS1,PS21,PS22,PS23,PS24,PS25,PSA,Pros,Pros1,THPH5,THPH6,Vitamin K-dependent protein S
|
| Uniprot Accession |
Q08761,P07224,P07225,Q28520,P53813
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Complement and coagulation cascades
|
| Gene Ensembl |
ENSECAG00000016509, ENSMUSG00000022912, ENSBTAG00000023652, ENSCAFG00845030582, ENSG00000184500, ENSMMUG00000020334
|
Pre-made viral vector of PROS1 cDNA Clones/ORF Plasmid
PROS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5627 | Pre-made Human PROS1/PSA/PROS siRNA oligo Duplex | 5627 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81750 | Pre-made Rat Pros1/Pros siRNA oligo Duplex | 81750 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19128 | Pre-made Mouse Pros1 siRNA oligo Duplex | 19128 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694845 | Pre-made Cynomolgus/Rhesus macaque PROS1 siRNA oligo Duplex | 694845 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085823 | Pre-made Cat/Feline PROS1 siRNA oligo Duplex | 101085823 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478529 | Pre-made Dog/Canine PROS1 siRNA oligo Duplex | 478529 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282006 | Pre-made Bovines/Cattle PROS1 siRNA oligo Duplex | 282006 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072912 | Pre-made Equine/Horse PROS1 siRNA oligo Duplex | 100072912 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PROS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1407-Ab | Human | Anti-Human PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1407-Ab | Rat | Anti-Rat PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1407-Ab | Mouse | Anti-Mouse PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1407-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1407-Ab | Cat/Feline | Anti-Cat/Feline PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1407-Ab | Dog/Canine | Anti-Dog/Canine PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1407-Ab | Bovines/Cattle | Anti-Bovines/Cattle PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1407-Ab | Equine/Horse | Anti-Equine/Horse PROS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PROS1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1407-Ag | Human | Human PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1407-Ag | Rat | Rat PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1407-Ag | Mouse | Mouse PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1407-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1407-Ag | Cat/Feline | Cat/Feline PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1407-Ag | Dog/Canine | Dog/Canine PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1407-Ag | Bovines/Cattle | Bovines/Cattle PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1407-Ag | Equine/Horse | Equine/Horse PROS1 VLP (virus-like particle) | HEK293 | Products Developing |
