Explore PON2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP1398
|
| Target Name |
PON2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5445
|
| Gene ID |
100062686 (Equus caballus), 101094492 (Felis catus), 281417 (Bos taurus), 296851 (Rattus norvegicus)
330260 (Mus musculus), 403855 (Canis lupus familiaris), 5445 (Homo sapiens), 699107 (Macaca mulatta)
|
| Target Alternative Names |
6330405I24Rik,Aromatic esterase 2 (A-esterase 2),PON 2,PON2,Pon2,Serum aryldialkylphosphatase 2,Serum paraoxonase/arylesterase 2
|
| Uniprot Accession |
Q58DS7,Q6AXM8,Q62086,P54832,Q15165
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSECAG00000010414, ENSBTAG00000008361, ENSMUSG00000032667, ENSCAFG00845020811, ENSG00000105854, ENSMMUG00000008014
|
Pre-made viral vector of PON2 cDNA Clones/ORF Plasmid
PON2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5445 | Pre-made Human PON2 siRNA oligo Duplex | 5445 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296851 | Pre-made Rat Pon2 siRNA oligo Duplex | 296851 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo330260 | Pre-made Mouse Pon2/6330405I24Rik siRNA oligo Duplex | 330260 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699107 | Pre-made Cynomolgus/Rhesus macaque PON2 siRNA oligo Duplex | 699107 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094492 | Pre-made Cat/Feline PON2 siRNA oligo Duplex | 101094492 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403855 | Pre-made Dog/Canine PON2 siRNA oligo Duplex | 403855 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281417 | Pre-made Bovines/Cattle PON2 siRNA oligo Duplex | 281417 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062686 | Pre-made Equine/Horse PON2 siRNA oligo Duplex | 100062686 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PON2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1398-Ab | Human | Anti-Human PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1398-Ab | Rat | Anti-Rat PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1398-Ab | Mouse | Anti-Mouse PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1398-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1398-Ab | Cat/Feline | Anti-Cat/Feline PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1398-Ab | Dog/Canine | Anti-Dog/Canine PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1398-Ab | Bovines/Cattle | Anti-Bovines/Cattle PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1398-Ab | Equine/Horse | Anti-Equine/Horse PON2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PON2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1398-Ag | Human | Human PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1398-Ag | Rat | Rat PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1398-Ag | Mouse | Mouse PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1398-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1398-Ag | Cat/Feline | Cat/Feline PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1398-Ag | Dog/Canine | Dog/Canine PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1398-Ag | Bovines/Cattle | Bovines/Cattle PON2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1398-Ag | Equine/Horse | Equine/Horse PON2 VLP (virus-like particle) | HEK293 | Products Developing |
