Explore iPLA2/PLA2G6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
| Target ID |
GM-MP1380
|
| Target Name |
iPLA2/PLA2G6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8398
|
| Gene ID |
100055064 (Equus caballus), 101095350 (Felis catus), 360426 (Rattus norvegicus), 481256 (Canis lupus familiaris)
53357 (Mus musculus), 535381 (Bos taurus), 700184 (Macaca mulatta), 8398 (Homo sapiens)
|
| Target Alternative Names |
PLA2G6,Pla2g6,iPla2,PNPLA9,GVI PLA2,caI-PLA2,iPLA2-beta,iPLA2,iPLA2beta,iPLA(2)beta,GVI,PLA2,INAD1,NBIA2,NBIA2A,NBIA2B,PARK14,CaI-PLA2,IPLA2-VIA
|
| Uniprot Accession |
P97570,P97819,O60733
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways, Ras signaling pathway, Vascular smooth muscle contraction, Inflammatory mediator regulation of TRP channels, Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism
|
| Gene Ensembl |
ENSECAG00000020924, ENSCAFG00845024672, ENSMUSG00000042632, ENSBTAG00000014015, ENSMMUG00000002701, ENSG00000184381
|
| Target Classification |
|
Pre-made viral vector of iPLA2/PLA2G6 cDNA Clones/ORF Plasmid
iPLA2/PLA2G6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8398 | Pre-made Human PLA2G6/GVI/PLA2 siRNA oligo Duplex | 8398 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360426 | Pre-made Rat Pla2g6/iPla2/PNPLA9 siRNA oligo Duplex | 360426 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo53357 | Pre-made Mouse Pla2g6/iPLA2/PNPLA9 siRNA oligo Duplex | 53357 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700184 | Pre-made Cynomolgus/Rhesus macaque PLA2G6 siRNA oligo Duplex | 700184 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095350 | Pre-made Cat/Feline PLA2G6 siRNA oligo Duplex | 101095350 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481256 | Pre-made Dog/Canine PLA2G6 siRNA oligo Duplex | 481256 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535381 | Pre-made Bovines/Cattle PLA2G6 siRNA oligo Duplex | 535381 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055064 | Pre-made Equine/Horse PLA2G6 siRNA oligo Duplex | 100055064 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
iPLA2/PLA2G6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1380-Ab | Human | Anti-Human iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1380-Ab | Rat | Anti-Rat iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1380-Ab | Mouse | Anti-Mouse iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1380-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1380-Ab | Cat/Feline | Anti-Cat/Feline iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1380-Ab | Dog/Canine | Anti-Dog/Canine iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1380-Ab | Bovines/Cattle | Anti-Bovines/Cattle iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1380-Ab | Equine/Horse | Anti-Equine/Horse iPLA2/PLA2G6 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
iPLA2/PLA2G6 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1380-Ag | Human | Human iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1380-Ag | Rat | Rat iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1380-Ag | Mouse | Mouse iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1380-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1380-Ag | Cat/Feline | Cat/Feline iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1380-Ag | Dog/Canine | Dog/Canine iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1380-Ag | Bovines/Cattle | Bovines/Cattle iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1380-Ag | Equine/Horse | Equine/Horse iPLA2/PLA2G6 VLP (virus-like particle) | HEK293 | Products Developing |
