Explore Polycystin 2/PKD2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
| Target ID |
GM-MP1376
|
| Target Name |
Polycystin 2/PKD2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5311
|
| Gene ID |
100063439 (Equus caballus), 101098948 (Felis catus), 18764 (Mus musculus), 487852 (Canis lupus familiaris)
498328 (Rattus norvegicus), 530393 (Bos taurus), 5311 (Homo sapiens), 702179 (Macaca mulatta)
|
| Target Alternative Names |
APKD2,Autosomal dominant polycystic kidney disease type II protein,C030034P18Rik,PC2,PKD2,PKD4,Pc-2,Pkd2,Polycystic kidney disease 2 protein,Polycystin 2,Polycystin-2,Polycystwin,R48321,RGD1559992,TRPP2,Transient receptor potential cation channel subfamily P member 2,Trpp2
|
| Uniprot Accession |
O35245,Q4GZT3,Q13563
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000024033, ENSMUSG00000034462, ENSCAFG00845016245, ENSBTAG00000020031, ENSG00000118762, ENSMMUG00000008795
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of Polycystin 2/PKD2 cDNA Clones/ORF Plasmid
Polycystin 2/PKD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5311 | Pre-made Human PKD2/PC2/PKD4 siRNA oligo Duplex | 5311 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498328 | Pre-made Rat Pkd2/Trpp2/RGD1559992 siRNA oligo Duplex | 498328 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18764 | Pre-made Mouse Pkd2/PC2/TRPP2 siRNA oligo Duplex | 18764 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702179 | Pre-made Cynomolgus/Rhesus macaque PKD2 siRNA oligo Duplex | 702179 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098948 | Pre-made Cat/Feline PKD2 siRNA oligo Duplex | 101098948 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487852 | Pre-made Dog/Canine PKD2/PC2 siRNA oligo Duplex | 487852 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo530393 | Pre-made Bovines/Cattle PKD2 siRNA oligo Duplex | 530393 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063439 | Pre-made Equine/Horse PKD2 siRNA oligo Duplex | 100063439 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Polycystin 2/PKD2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1376-Ab | Human | Anti-Human Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1376-Ab | Rat | Anti-Rat Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1376-Ab | Mouse | Anti-Mouse Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1376-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1376-Ab | Cat/Feline | Anti-Cat/Feline Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1376-Ab | Dog/Canine | Anti-Dog/Canine Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1376-Ab | Bovines/Cattle | Anti-Bovines/Cattle Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1376-Ab | Equine/Horse | Anti-Equine/Horse Polycystin 2/PKD2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Polycystin 2/PKD2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1376-Ag | Human | Human Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1376-Ag | Rat | Rat Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1376-Ag | Mouse | Mouse Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1376-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1376-Ag | Cat/Feline | Cat/Feline Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1376-Ag | Dog/Canine | Dog/Canine Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1376-Ag | Bovines/Cattle | Bovines/Cattle Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1376-Ag | Equine/Horse | Equine/Horse Polycystin 2/PKD2 VLP (virus-like particle) | HEK293 | Products Developing |
