Explore PILRA gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP1371
|
| Target Name |
PILRA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
29992
|
| Gene ID |
100137734 (Bos taurus), 102149215 (Equus caballus), 102902076 (Felis catus), 231805 (Mus musculus)
29992 (Homo sapiens), 489841 (Canis lupus familiaris), 721913 (Macaca mulatta)
|
| Target Alternative Names |
Cell surface receptor FDF03,FDF03,Inhibitory receptor PILR-alpha,PILRA,Paired immunoglobulin-like type 2 receptor alpha,Pilra
|
| Uniprot Accession |
Q2YFS3,Q9UKJ1
|
| Protein Sub-location |
Transmembrane Protein
|
| Gene Ensembl |
ENSBTAG00000001066, ENSECAG00000033857, ENSMUSG00000046245, ENSG00000085514, ENSCAFG00845002176, ENSMMUG00000043070
|
PILRA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo29992 | Pre-made Human PILRA/FDF03 siRNA oligo Duplex | 29992 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo231805 | Pre-made Mouse Pilra/FDF03 siRNA oligo Duplex | 231805 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721913 | Pre-made Cynomolgus/Rhesus macaque PILRA siRNA oligo Duplex | 721913 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102902076 | Pre-made Cat/Feline PILRA siRNA oligo Duplex | 102902076 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489841 | Pre-made Dog/Canine PILRA siRNA oligo Duplex | 489841 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100137734 | Pre-made Bovines/Cattle PILRA siRNA oligo Duplex | 100137734 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149215 | Pre-made Equine/Horse PILRA siRNA oligo Duplex | 102149215 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PILRA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1371-Ab | Human | Anti-Human PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1371-Ab | Mouse | Anti-Mouse PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1371-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1371-Ab | Cat/Feline | Anti-Cat/Feline PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1371-Ab | Dog/Canine | Anti-Dog/Canine PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1371-Ab | Bovines/Cattle | Anti-Bovines/Cattle PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1371-Ab | Equine/Horse | Anti-Equine/Horse PILRA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PILRA VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1371-Ag | Human | Human PILRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1371-Ag | Mouse | Mouse PILRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1371-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PILRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1371-Ag | Cat/Feline | Cat/Feline PILRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1371-Ag | Dog/Canine | Dog/Canine PILRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1371-Ag | Bovines/Cattle | Bovines/Cattle PILRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1371-Ag | Equine/Horse | Equine/Horse PILRA VLP (virus-like particle) | HEK293 | Products Developing |
