Explore OPCML gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
| Target ID |
GM-MP0920
|
| Target Name |
OPCML
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4978
|
| Gene ID |
100064790 (Equus caballus), 100686219 (Canis lupus familiaris), 101094787 (Felis catus), 116597 (Rattus norvegicus) 281957 (Bos taurus), 330908 (Mus musculus), 4978 (Homo sapiens), 693404 (Macaca mulatta)
|
| Target Alternative Names |
2900075O15Rik,3732419F12,B930023M13Rik,C230027C17,Gm181,IGLON1,IgLON family member 1,OBCAM,OPCM,OPCML,Obcam,Opcml,Opioid-binding cell adhesion molecule,Opioid-binding protein/cell adhesion molecule
|
| Uniprot Accession |
P32736,P11834,Q14982
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer, Lung Cancer
|
| Gene Ensembl |
ENSECAG00000009233, ENSCAFG00845005767, ENSBTAG00000020769, ENSMUSG00000062257, ENSG00000183715, ENSMMUG00000047242
|
Pre-made viral vector of OPCML cDNA Clones/ORF Plasmid
OPCML siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4978 | Pre-made Human OPCML/OPCM/OBCAM siRNA oligo Duplex | 4978 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116597 | Pre-made Rat Opcml siRNA oligo Duplex | 116597 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo330908 | Pre-made Mouse Opcml/Gm181/Obcam siRNA oligo Duplex | 330908 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693404 | Pre-made Cynomolgus/Rhesus macaque OPCML siRNA oligo Duplex | 693404 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094787 | Pre-made Cat/Feline OPCML siRNA oligo Duplex | 101094787 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100686219 | Pre-made Dog/Canine OPCML siRNA oligo Duplex | 100686219 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281957 | Pre-made Bovines/Cattle OPCML/OBCAM siRNA oligo Duplex | 281957 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064790 | Pre-made Equine/Horse OPCML siRNA oligo Duplex | 100064790 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OPCML antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0920-Ab | Human | Anti-Human OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0920-Ab | Rat | Anti-Rat OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0920-Ab | Mouse | Anti-Mouse OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0920-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0920-Ab | Cat/Feline | Anti-Cat/Feline OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0920-Ab | Dog/Canine | Anti-Dog/Canine OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0920-Ab | Bovines/Cattle | Anti-Bovines/Cattle OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0920-Ab | Equine/Horse | Anti-Equine/Horse OPCML monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
OPCML VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0920-Ag | Human | Human OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0920-Ag | Rat | Rat OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0920-Ag | Mouse | Mouse OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0920-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0920-Ag | Cat/Feline | Cat/Feline OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0920-Ag | Dog/Canine | Dog/Canine OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0920-Ag | Bovines/Cattle | Bovines/Cattle OPCML VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0920-Ag | Equine/Horse | Equine/Horse OPCML VLP (virus-like particle) | HEK293 | Products Developing |