OCLN Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore OCLN gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]

Target ID	GM-MP0916
Target Name	OCLN
Gene Group ldentifer （Target Gene ID in Homo species)	100506658
Gene ID	100073306 (Equus caballus), 100506658 (Homo sapiens), 101089577 (Felis catus), 18260 (Mus musculus) 403844 (Canis lupus familiaris), 512405 (Bos taurus), 700504 (Macaca mulatta), 83497 (Rattus norvegicus)
Target Alternative Names	BLCPMG,OCLN,Occludin,Ocl,Ocln,PPP1R115,PTORCH1
Uniprot Accession	Q16625,Q61146,Q28269,Q6P6T5
Protein Sub-location	Transmembrane Protein
Disease	cancer
Disease from KEGG	Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Hepatitis C
Gene Ensembl	ENSECAG00000009118, ENSG00000197822, ENSMUSG00000021638, ENSCAFG00845012752, ENSBTAG00000000561, ENSMMUG00000006216

Pre-made viral vector of OCLN cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP001093	Human OCLN/BLCPMG/PPP1R115 Lentivirus plasmid	NM_002538	100506658	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP001093	Human OCLN/BLCPMG/PPP1R115 Lentivirus particle	NM_002538	100506658	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLV001069	Mouse Ocln/AI503564/Ocl Lentivirus plasmid	NM_008756.2	18260	Mouse	Lentivirus plasmid	null	Null	CMV	Detail
pGMLPm005039	Mouse Ocln/AI503564/Ocl Lentivirus plasmid	NM_008756.2	18260	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLV001069	Mouse Ocln/AI503564/Ocl Lentivirus particle	NM_008756.2	18260	Mouse	Lentivirus particle	null	Null	CMV	Detail
vGMLPm005039	Mouse Ocln/AI503564/Ocl Lentivirus particle	NM_008756.2	18260	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

OCLN siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo100506658	Pre-made Human OCLN/BLCPMG/PTORCH1 siRNA oligo Duplex	100506658	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo83497	Pre-made Rat Ocln siRNA oligo Duplex	83497	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo18260	Pre-made Mouse Ocln/Ocl siRNA oligo Duplex	18260	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo700504	Pre-made Cynomolgus/Rhesus macaque OCLN siRNA oligo Duplex	700504	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101089577	Pre-made Cat/Feline OCLN siRNA oligo Duplex	101089577	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo403844	Pre-made Dog/Canine OCLN siRNA oligo Duplex	403844	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo512405	Pre-made Bovines/Cattle OCLN siRNA oligo Duplex	512405	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100073306	Pre-made Equine/Horse OCLN siRNA oligo Duplex	100073306	Equine/Horse	In-vitro grade; in-vivo grade	Detail

OCLN antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-MP0916-Ab	Human	Anti-Human OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-rg-MP0916-Ab	Rat	Anti-Rat OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-mg-MP0916-Ab	Mouse	Anti-Mouse OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-cynog-MP0916-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-felg-MP0916-Ab	Cat/Feline	Anti-Cat/Feline OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-cang-MP0916-Ab	Dog/Canine	Anti-Dog/Canine OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-bovg-MP0916-Ab	Bovines/Cattle	Anti-Bovines/Cattle OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail
GM-Tg-equg-MP0916-Ab	Equine/Horse	Anti-Equine/Horse OCLN monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail

OCLN VLP (virus-like particle)/protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-MP0916-Ag	Human	Human OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-rg-MP0916-Ag	Rat	Rat OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-mg-MP0916-Ag	Mouse	Mouse OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-cynog-MP0916-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-felg-MP0916-Ag	Cat/Feline	Cat/Feline OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-cang-MP0916-Ag	Dog/Canine	Dog/Canine OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-bovg-MP0916-Ag	Bovines/Cattle	Bovines/Cattle OCLN VLP (virus-like particle)	HEK293	Products Developing
GM-Tg-equg-MP0916-Ag	Equine/Horse	Equine/Horse OCLN VLP (virus-like particle)	HEK293	Products Developing