Explore NRXN1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016]
| Target ID |
GM-MP0908
|
| Target Name |
NRXN1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9378
|
| Gene ID |
100052908 (Equus caballus), 101084531 (Felis catus), 18189 (Mus musculus), 281950 (Bos taurus) 474589 (Canis lupus familiaris), 60391 (Rattus norvegicus), 619185 (Macaca mulatta), 9378 (Homo sapiens)
|
| Target Alternative Names |
1700062G21Rik,9330127H16Rik,A230068P09Rik,Hs.22998,NRXN1,Nrxn1,Nrxn1b,PTHSL2,SCZD17,mKIAA0578
|
| Uniprot Accession |
P0DI97,Q9CS84,Q28142,Q28146,Q63372,Q63373,P58400,Q9ULB1
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000009451, ENSMUSG00000024109, ENSBTAG00000046199, ENSCAFG00845006920, ENSMMUG00000038179, ENSG00000179915
|
Pre-made viral vector of NRXN1 cDNA Clones/ORF Plasmid
NRXN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9378 | Pre-made Human NRXN1/PTHSL2/SCZD17 siRNA oligo Duplex | 9378 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60391 | Pre-made Rat Nrxn1/Nrxn1b siRNA oligo Duplex | 60391 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18189 | Pre-made Mouse Nrxn1/mKIAA0578/1700062G21Rik siRNA oligo Duplex | 18189 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo619185 | Pre-made Cynomolgus/Rhesus macaque NRXN1 siRNA oligo Duplex | 619185 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084531 | Pre-made Cat/Feline NRXN1 siRNA oligo Duplex | 101084531 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474589 | Pre-made Dog/Canine NRXN1 siRNA oligo Duplex | 474589 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281950 | Pre-made Bovines/Cattle NRXN1 siRNA oligo Duplex | 281950 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052908 | Pre-made Equine/Horse NRXN1 siRNA oligo Duplex | 100052908 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NRXN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0908-Ab | Human | Anti-Human NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0908-Ab | Rat | Anti-Rat NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0908-Ab | Mouse | Anti-Mouse NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0908-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0908-Ab | Cat/Feline | Anti-Cat/Feline NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0908-Ab | Dog/Canine | Anti-Dog/Canine NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0908-Ab | Bovines/Cattle | Anti-Bovines/Cattle NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0908-Ab | Equine/Horse | Anti-Equine/Horse NRXN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NRXN1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0908-Ag | Human | Human NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0908-Ag | Rat | Rat NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0908-Ag | Mouse | Mouse NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0908-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0908-Ag | Cat/Feline | Cat/Feline NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0908-Ag | Dog/Canine | Dog/Canine NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0908-Ag | Bovines/Cattle | Bovines/Cattle NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0908-Ag | Equine/Horse | Equine/Horse NRXN1 VLP (virus-like particle) | HEK293 | Products Developing |