Explore NRG2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010]
| Target ID |
GM-MP0904
|
| Target Name |
NRG2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9542
|
| Gene ID |
100042150 (Mus musculus), 100072444 (Equus caballus), 101090986 (Felis catus), 432361 (Rattus norvegicus)
487158 (Canis lupus familiaris), 694995 (Macaca mulatta), 783452 (Bos taurus), 9542 (Homo sapiens)
|
| Target Alternative Names |
DON1,Don1,HRG2,NRG2,NTAK,NTAK alpha1,NTAK alpha2a,NTAK_alpha2a,Nrg2,Ntak,Pro-NRG2,Pro-neuregulin-2,membrane-bound isoform
|
| Uniprot Accession |
P56974,O35569,O14511
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease from KEGG |
EGFR tyrosine kinase inhibitor resistance, ErbB signaling pathway
|
| Gene Ensembl |
ENSMUSG00000060275, ENSECAG00000013341, ENSMMUG00000010301, ENSBTAG00000010689, ENSG00000158458
|
NRG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9542 | Pre-made Human NRG2/DON1/HRG2 siRNA oligo Duplex | 9542 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo432361 | Pre-made Rat Nrg2/Ntak/NTAK alpha1 siRNA oligo Duplex | 432361 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100042150 | Pre-made Mouse Nrg2/Don1/NTAK siRNA oligo Duplex | 100042150 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694995 | Pre-made Cynomolgus/Rhesus macaque NRG2 siRNA oligo Duplex | 694995 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090986 | Pre-made Cat/Feline NRG2 siRNA oligo Duplex | 101090986 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487158 | Pre-made Dog/Canine NRG2 siRNA oligo Duplex | 487158 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo783452 | Pre-made Bovines/Cattle NRG2 siRNA oligo Duplex | 783452 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072444 | Pre-made Equine/Horse NRG2 siRNA oligo Duplex | 100072444 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NRG2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0904-Ab | Human | Anti-Human NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP0904-Ab | Rat | Anti-Rat NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP0904-Ab | Mouse | Anti-Mouse NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP0904-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-MP0904-Ab | Cat/Feline | Anti-Cat/Feline NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP0904-Ab | Dog/Canine | Anti-Dog/Canine NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP0904-Ab | Bovines/Cattle | Anti-Bovines/Cattle NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP0904-Ab | Equine/Horse | Anti-Equine/Horse NRG2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
NRG2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0904-Ag | Human | Human NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0904-Ag | Rat | Rat NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0904-Ag | Mouse | Mouse NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0904-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0904-Ag | Cat/Feline | Cat/Feline NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0904-Ag | Dog/Canine | Dog/Canine NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0904-Ag | Bovines/Cattle | Bovines/Cattle NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0904-Ag | Equine/Horse | Equine/Horse NRG2 VLP (virus-like particle) | HEK293 | Products Developing |
