Explore Nephrin/NPHS1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.[provided by RefSeq, Oct 2009]
| Target ID |
GM-MP0898
|
| Target Name |
Nephrin/NPHS1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4868
|
| Gene ID |
100147013 (Equus caballus), 101101018 (Felis catus), 484571 (Canis lupus familiaris), 4868 (Homo sapiens)
519706 (Bos taurus), 54631 (Mus musculus), 64563 (Rattus norvegicus), 718929 (Macaca mulatta)
|
| Target Alternative Names |
NPHS1,Nphs1,CNF,NPHN,nephrin,NephrinB
|
| Uniprot Accession |
O60500,Q9QZS7,Q9R044
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000012641, ENSCAFG00845001053, ENSG00000161270, ENSBTAG00000007821, ENSMUSG00000006649, ENSMMUG00000019749
|
| Target Classification |
|
Nephrin/NPHS1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4868 | Pre-made Human NPHS1/CNF/NPHN siRNA oligo Duplex | 4868 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64563 | Pre-made Rat Nphs1 siRNA oligo Duplex | 64563 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54631 | Pre-made Mouse Nphs1/nephrin/NephrinB siRNA oligo Duplex | 54631 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718929 | Pre-made Cynomolgus/Rhesus macaque NPHS1 siRNA oligo Duplex | 718929 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101018 | Pre-made Cat/Feline NPHS1 siRNA oligo Duplex | 101101018 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484571 | Pre-made Dog/Canine NPHS1 siRNA oligo Duplex | 484571 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519706 | Pre-made Bovines/Cattle NPHS1 siRNA oligo Duplex | 519706 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147013 | Pre-made Equine/Horse NPHS1 siRNA oligo Duplex | 100147013 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Nephrin/NPHS1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0898-Ab | Human | Anti-Human Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0898-Ab | Rat | Anti-Rat Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0898-Ab | Mouse | Anti-Mouse Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0898-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0898-Ab | Cat/Feline | Anti-Cat/Feline Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0898-Ab | Dog/Canine | Anti-Dog/Canine Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0898-Ab | Bovines/Cattle | Anti-Bovines/Cattle Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0898-Ab | Equine/Horse | Anti-Equine/Horse Nephrin/NPHS1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Nephrin/NPHS1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0898-Ag | Human | Human Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0898-Ag | Rat | Rat Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0898-Ag | Mouse | Mouse Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0898-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0898-Ag | Cat/Feline | Cat/Feline Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0898-Ag | Dog/Canine | Dog/Canine Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0898-Ag | Bovines/Cattle | Bovines/Cattle Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0898-Ag | Equine/Horse | Equine/Horse Nephrin/NPHS1 VLP (virus-like particle) | HEK293 | Products Developing |
