Explore Neurofascin/NFASC gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009]
| Target ID |
GM-MP0876
|
| Target Name |
Neurofascin/NFASC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23114
|
| Gene ID |
100054575 (Equus caballus), 101083317 (Felis catus), 116690 (Rattus norvegicus), 23114 (Homo sapiens)
269116 (Mus musculus), 488565 (Canis lupus familiaris), 512796 (Bos taurus), 699444 (Macaca mulatta)
|
| Target Alternative Names |
D430023G06Rik,NEDCPMD,NF,NFASC,NRCAML,Neurofascin,Nfasc,mKIAA0756
|
| Uniprot Accession |
P97685,O94856,Q810U3
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000011985, ENSG00000163531, ENSMUSG00000026442, ENSCAFG00845023882, ENSBTAG00000045895, ENSMMUG00000017508
|
Neurofascin/NFASC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23114 | Pre-made Human NFASC/NF/NRCAML siRNA oligo Duplex | 23114 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116690 | Pre-made Rat Nfasc/NF siRNA oligo Duplex | 116690 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo269116 | Pre-made Mouse Nfasc/NF/mKIAA0756 siRNA oligo Duplex | 269116 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699444 | Pre-made Cynomolgus/Rhesus macaque NFASC siRNA oligo Duplex | 699444 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083317 | Pre-made Cat/Feline NFASC siRNA oligo Duplex | 101083317 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488565 | Pre-made Dog/Canine NFASC siRNA oligo Duplex | 488565 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512796 | Pre-made Bovines/Cattle NFASC siRNA oligo Duplex | 512796 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054575 | Pre-made Equine/Horse NFASC siRNA oligo Duplex | 100054575 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Neurofascin/NFASC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0876-Ab | Human | Anti-Human Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0876-Ab | Rat | Anti-Rat Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0876-Ab | Mouse | Anti-Mouse Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0876-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0876-Ab | Cat/Feline | Anti-Cat/Feline Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0876-Ab | Dog/Canine | Anti-Dog/Canine Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0876-Ab | Bovines/Cattle | Anti-Bovines/Cattle Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0876-Ab | Equine/Horse | Anti-Equine/Horse Neurofascin/NFASC monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Neurofascin/NFASC VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0876-Ag | Human | Human Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0876-Ag | Rat | Rat Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0876-Ag | Mouse | Mouse Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0876-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0876-Ag | Cat/Feline | Cat/Feline Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0876-Ag | Dog/Canine | Dog/Canine Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0876-Ag | Bovines/Cattle | Bovines/Cattle Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0876-Ag | Equine/Horse | Equine/Horse Neurofascin/NFASC VLP (virus-like particle) | HEK293 | Products Developing |
