Explore NEU1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0874
|
| Target Name |
NEU1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4758
|
| Gene ID |
100059083 (Equus caballus), 101091282 (Felis catus), 18010 (Mus musculus), 24591 (Rattus norvegicus)
4758 (Homo sapiens), 481717 (Canis lupus familiaris), 505554 (Bos taurus), 716740 (Macaca mulatta)
|
| Target Alternative Names |
Acetylneuraminyl hydrolase,Aglp,Apl,Bat-7,Bat7,G9,G9 sialidase,Lysosomal sialidase,Map-2,N-acetyl-alpha-neuraminidase 1,NANH,NEU,NEU1,Neu,Neu-1,Neu1,SIAL1,Sialidase-1
|
| Uniprot Accession |
O35657,Q99PW3,Q99519,A6BMK7
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways, Lysosome, Sphingolipid metabolism
|
| Gene Ensembl |
ENSMUSG00000007038, ENSG00000204386, ENSBTAG00000005674, ENSMMUG00000021707
|
Pre-made viral vector of NEU1 cDNA Clones/ORF Plasmid
NEU1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4758 | Pre-made Human NEU1/NEU/NANH siRNA oligo Duplex | 4758 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24591 | Pre-made Rat Neu1 siRNA oligo Duplex | 24591 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18010 | Pre-made Mouse Neu1/G9/Apl siRNA oligo Duplex | 18010 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716740 | Pre-made Cynomolgus/Rhesus macaque NEU1 siRNA oligo Duplex | 716740 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091282 | Pre-made Cat/Feline NEU1 siRNA oligo Duplex | 101091282 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481717 | Pre-made Dog/Canine NEU1 siRNA oligo Duplex | 481717 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505554 | Pre-made Bovines/Cattle NEU1 siRNA oligo Duplex | 505554 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059083 | Pre-made Equine/Horse NEU1 siRNA oligo Duplex | 100059083 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NEU1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0874-Ab | Human | Anti-Human NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0874-Ab | Rat | Anti-Rat NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0874-Ab | Mouse | Anti-Mouse NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0874-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0874-Ab | Cat/Feline | Anti-Cat/Feline NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0874-Ab | Dog/Canine | Anti-Dog/Canine NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0874-Ab | Bovines/Cattle | Anti-Bovines/Cattle NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0874-Ab | Equine/Horse | Anti-Equine/Horse NEU1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NEU1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0874-Ag | Human | Human NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0874-Ag | Rat | Rat NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0874-Ag | Mouse | Mouse NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0874-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0874-Ag | Cat/Feline | Cat/Feline NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0874-Ag | Dog/Canine | Dog/Canine NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0874-Ag | Bovines/Cattle | Bovines/Cattle NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0874-Ag | Equine/Horse | Equine/Horse NEU1 VLP (virus-like particle) | HEK293 | Products Developing |
