Explore NCR3/NKp30/CD337 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
| Target ID |
GM-MP0869
|
| Target Name |
NCR3/NKp30/CD337
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
259197
|
| Gene ID |
100058447 (Equus caballus), 101100052 (Felis catus), 259197 (Homo sapiens), 294251 (Rattus norvegicus) 513769 (Bos taurus), 607220 (Canis lupus familiaris), 715574 (Macaca mulatta)
|
| Target Alternative Names |
1C7,Activating natural killer receptor p30,CD337,LY117,MALS,NCR3,NKp30,NKp30),Natural cytotoxicity triggering receptor 3,Natural killer cell p30-related protein (NK-p30,Ncr3,Nkp30
|
| Uniprot Accession |
O14931,Q8CFD9,Q8MJ02
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity
|
| Gene Ensembl |
ENSECAG00000051610, ENSG00000204475, ENSBTAG00000018343, ENSMMUG00000008854
|
Pre-made viral vector of NCR3/NKp30/CD337 cDNA Clones/ORF Plasmid
NCR3/NKp30/CD337 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo259197 | Pre-made Human NCR3/1C7/MALS siRNA oligo Duplex | 259197 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294251 | Pre-made Rat Ncr3/1C7/Nkp30 siRNA oligo Duplex | 294251 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715574 | Pre-made Cynomolgus/Rhesus macaque NCR3/NKp30 siRNA oligo Duplex | 715574 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100052 | Pre-made Cat/Feline NCR3 siRNA oligo Duplex | 101100052 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607220 | Pre-made Dog/Canine NCR3/NKp30 siRNA oligo Duplex | 607220 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513769 | Pre-made Bovines/Cattle NCR3 siRNA oligo Duplex | 513769 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058447 | Pre-made Equine/Horse NCR3 siRNA oligo Duplex | 100058447 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NCR3/NKp30/CD337 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0869-Ab | Human | Anti-Human NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0869-Ab | Rat | Anti-Rat NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0869-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0869-Ab | Cat/Feline | Anti-Cat/Feline NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0869-Ab | Dog/Canine | Anti-Dog/Canine NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0869-Ab | Bovines/Cattle | Anti-Bovines/Cattle NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0869-Ab | Equine/Horse | Anti-Equine/Horse NCR3/NKp30/CD337 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NCR3/NKp30/CD337 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0869-Ag | Human | Human NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0869-Ag | Rat | Rat NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0869-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0869-Ag | Cat/Feline | Cat/Feline NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0869-Ag | Dog/Canine | Dog/Canine NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0869-Ag | Bovines/Cattle | Bovines/Cattle NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0869-Ag | Equine/Horse | Equine/Horse NCR3/NKp30/CD337 VLP (virus-like particle) | HEK293 | Products Developing |