Explore MICB gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
| Target ID |
GM-MP0814
|
| Target Name |
MICB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4277
|
| Gene ID |
123385743 (Felis catus), 4277 (Homo sapiens)
|
| Target Alternative Names |
MHC class I polypeptide-related sequence B,MIC-B,MICB,PERB11.2
|
| Uniprot Accession |
Q29980
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity, Kaposi sarcoma-associated herpesvirus infection
|
| Gene Ensembl |
ENSG00000204516
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of MICB cDNA Clones/ORF Plasmid
MICB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4277 | Pre-made Human MICB/PERB11.2 siRNA oligo Duplex | 4277 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo123385743 | Pre-made Cat/Feline MICB siRNA oligo Duplex | 123385743 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
MICB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0814-Ab | Human | Anti-Human MICB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-MP0814-Ab | Cat/Feline | Anti-Cat/Feline MICB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MICB VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0814-Ag | Human | Human MICB VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0814-Ag | Cat/Feline | Cat/Feline MICB VLP (virus-like particle) | HEK293 | Products Developing |
